Refractory Metastatic Colorectal Cancer
Conditions
Brief summary
ORR, defined as the proportion of patients with a complete response or partial response as assessed by RECIST 1.1 criteria.
Detailed description
01. DOR, defined as the time from initial objective radiographic response until disease progression or death, whichever occurs first., 02. PFS, defined as the time from randomization until disease progression or death, whichever occurs first., 03. OS, defined as the time from randomization until death due to any cause.
Interventions
DRUGBOTENSILIMAB
DRUGStivarga 40 mg film-coated tablets.
DRUGBALSTILIMAB
Sponsors
Agenus Inc.
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ORR, defined as the proportion of patients with a complete response or partial response as assessed by RECIST 1.1 criteria. | — |
Secondary
| Measure | Time frame |
|---|---|
| 01. DOR, defined as the time from initial objective radiographic response until disease progression or death, whichever occurs first., 02. PFS, defined as the time from randomization until disease progression or death, whichever occurs first., 03. OS, defined as the time from randomization until death due to any cause. | — |
Countries
Belgium, France, Italy, Spain
Outcome results
None listed