STOP-COPD Standard vs Targeted Oxygen Therapy Prehospital for Chronic Obstructive Pulmonary Disease

Conditions

Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Brief summary

30-day mortality

Detailed description

24-hour mortality, 7-day mortality, Length of hospitalization, ICU admission rate, Length of ICU admission, In-hospital need for NIV within 24 hours, 7 days and 30 days, Time to NIV, In-hospital need for invasive mechanical ventilation within 24 hours, 7 days and 30 days, Time to invasive ventilation, Proportion of patients with respiratory acidosis on arrival to hospital, The degree of acidosis based on the pH-value, Patient experienced dyspnoea on a verbal rating scale 0-10, Readmission rate, Time to readmission

Jensen ASR, Valentin JB, Mulvad MG, Hagenau V, Skaarup SH, Johnsen SP, Johnsen SP, Væggemose U, Gude MF.

2024-01-259 citations

10.1186/s13063-024-07920-5

Interventions

DRUGBerodual

DRUGinhalationsvæske til nebulisator

DRUGopløsning

DRUGSalbutamol ”TEVA”

DRUGMedicinsk Luft ”Air Liquide” 100%

DRUGmedicinsk gas

DRUGkomprimeret

DRUGMedicinsk Oxygen ”Air Liquide” 100 %

DRUGmedicinsk gas komprimeret

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Design outcomes

Primary

Measure	Time frame
30-day mortality	—

Secondary

Measure	Time frame
24-hour mortality, 7-day mortality, Length of hospitalization, ICU admission rate, Length of ICU admission, In-hospital need for NIV within 24 hours, 7 days and 30 days, Time to NIV, In-hospital need for invasive mechanical ventilation within 24 hours, 7 days and 30 days, Time to invasive ventilation, Proportion of patients with respiratory acidosis on arrival to hospital, The degree of acidosis based on the pH-value, Patient experienced dyspnoea on a verbal rating scale 0-10, Readmission rate, Time to readmission	—

Measure

Time frame

24-hour mortality, 7-day mortality, Length of hospitalization, ICU admission rate, Length of ICU admission, In-hospital need for NIV within 24 hours, 7 days and 30 days, Time to NIV, In-hospital need for invasive mechanical ventilation within 24 hours, 7 days and 30 days, Time to invasive ventilation, Proportion of patients with respiratory acidosis on arrival to hospital, The degree of acidosis based on the pH-value, Patient experienced dyspnoea on a verbal rating scale 0-10, Readmission rate, Time to readmission

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Countries

Denmark

Outcome results

None listed