None listed
Conditions
Brief summary
This study aims to compare two commonly used pain-relief techniques given during anterior cruciate ligament (ACL) reconstruction surgery using hamstring tendon grafts. After ACL surgery, some patients experience significant pain and require opioid pain medicines, which can have unwanted side effects. Participants undergoing ACL reconstruction at Hornsby Hospital will be randomly assigned to receive one of two regional anaesthetic techniques in addition to standard pain management: an adductor canal block with local anaesthetic infiltration, or an IPACK block with local anaesthetic infiltration. Both techniques are routinely used in clinical practice. The main aim of the study is to determine whether one technique leads to lower opioid use in the first week after surgery. The study will also compare pain levels, patient satisfaction, and knee-related recovery outcomes over the first three months following surgery. We hypothesise that patients receiving the IPACK block will require less opioid medication and experience better early pain control compared with those receiving the adductor canal block.
Interventions
Brief name: IPACK block plus local infiltration analgesia for postoperative analgesia following hamstring tendon anterior cruciate ligament reconstruction. Description of intervention(s): Participants allocated to the intervention group will receive an ultrasound-guided IPACK (Infiltration between the Popliteal Artery and Capsule of the Knee) block administered by a consultant anaesthetist experienced in ultrasound-guided regional anaesthesia. Timing: Single administration intraoperatively, immediately following induction of general anaesthesia and prior to surgical incision. Technique and dose: Under ultrasound guidance, a 20-gauge needle is inserted into the interspace between the popliteal artery and posterior capsule of the knee. Following negative aspiration, 20 mL of bupivacaine 0.25% is injected incrementally. Single dose; not repeated. Co-intervention (standardised for both groups): All participants additionally receive local infiltration analgesia (LIA) — bupivacaine 0.5% 20 mL infiltrated into peri-articular tissues at surgical completion prior to wound closure, plus ketorolac 30 mg intravenously intraoperatively. Standardised background analgesia (both groups): General anaesthesia, paracetamol 1 g four times daily (regular), oxycodone 5–10 mg orally every 4 hours as required, and intraoperative fentanyl titrated to haemodynamic response. Adherence: All blocks are performed to a standardised protocol by consultant anaesthetists trained in ultrasound-guided regional anaesthesia. Anaesthetic records are reviewed post-procedure to confirm adherence to technique and dosing.
Sponsors
Study design
Eligibility
Inclusion criteria
• Aged 16 to 75 years. • American Society of Anaesthesiologists physical status grade I or II. • Undergoing primary anterior cruciate ligament reconstruction using hamstring tendon autograft. • Able to provide informed consent. • Undergoing surgery at Hornsby Hospital.
Exclusion criteria
• Revision anterior cruciate ligament reconstruction. • Known allergy or contraindication to local anaesthetics, opioids, or study medications. • Chronic opioid use within the preceding 3 months. • Coagulopathy or bleeding disorder. • Severe hepatic or renal impairment. • History of alcohol or substance use disorder. • Inability to comply with study procedures or follow-up. • Refusal or inability to provide informed consent.