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Accuracy of early bedside echo for the rapid diagnosis of heart failure in dyspnoeic patients

Accuracy of early bedside echo for the rapid diagnosis of heart failure in dyspnoeic patients

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12626000564358
Enrollment
200
Registered
2026-05-04
Start date
2026-05-04
Completion date
2027-04-30
Last updated
2026-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Acute dyspnoea (shortness of breath) is the most common symptom in 30% of patients admitted acutely to General Medicine in New Zealand each year [approximately 8,000 patients]. However the differential diagnosis is broad, including heart failure, asthma, COPD, pulmonary embolism and pneumonia, and many elderly patients have multiple mechanisms for their dyspnoea. Heart failure - manifested as acute volume overload - is the commonest cause and requires urgent treatment usually with diuretics and oxygen. For the acute Emergency and Medical teams, the volume status of the patient is difficult to ascertain which means that some patients are either not treated or over-treated. We aim to undertake early bedside echo - also known as Point of Care Ultra Sound [POCUS] - in consecutively admitted patients with dyspnoea within 24 hours of their presentation to the Emergency Department. We hypothesise that the echo will add accuracy to our initial assessments of these patients, resulting in more appropriate, rapid correction of their blood volume and therefore improvement of their symptoms.

Interventions

We aim to undertake early bedside echo - also known as Point of Care Ultra Sound [POCUS] - in consecutively admitted patients with dyspnoea within 24 hours of their presentation to the Emergency Department. The Sonosite Edge II portable ultrasound [about 7 years old] which is carried in an over-shoulder bag and therefore can be moved around wards easily. In the Emergency Dept we use a trolley-based Sonosite device of similar vintage. We are hoping to replace our Sonosites later this year with

We aim to undertake early bedside echo - also known as Point of Care Ultra Sound [POCUS] - in consecutively admitted patients with dyspnoea within 24 hours of their presentation to the Emergency Department. The Sonosite Edge II portable ultrasound [about 7 years old] which is carried in an over-shoulder bag and therefore can be moved around wards easily. In the Emergency Dept we use a trolley-based Sonosite device of similar vintage. We are hoping to replace our Sonosites later this year with a Mindray MX5 compact ultrasound system which gives similar quality pictures. Patients will be informed about the study and asked to provide consent. Patients will then be divided into 2 groups whereby patients are given a study number [in order of presentation] and then randomly allotted into: group 1 in whom bedside echo is undertaken immediately and the echo results are shared with the medical team, and group 2, in whom no immediate bedside echo is done and the medical management is based only on standard criteria for volume overload/heart failure. Each bedside echo consists of imaging the heart, inferior vena cava, and the lungs, all of which takes 10 minutes. Images will be stored on our PAX system for later reference. Echoes will be done, or directly supervised by, the principle investigators David Jardine and Jacques Loubser. A data sheet will be filled out by the investigator detailing important results including speed of recovery, length of stay, and echo results. During the admission “recovery indices” will be recorded by the medical teams and later assessed by an investigator blinded to the bedside echo results. The final diagnosis relating to the cause of dyspnoea [volume overload or something else] will be made by the medical teams caring for the patient at time of discharge. Depending on these results, the medical team caring for the patient will document a working diagnosis of volume overload [or otherwise] within 24 hours of admission. Subsequent investigations and treatment will be undertaken as indicated in both groups. Patients presenting with dyspnoea may require further relevant imaging, particularly if they do not respond to treatment [eg diuretics, antibiotics, anticoagulation]. These investigations might include formal echo, repeat chest X-ray, CT chest, and further blood tests. It may be that patients in the control arm require more investigations during their stay so this is important data.

Sponsors

Health New Zealand Canterbury
Lead SponsorGovernment body

Study design

Allocation
Randomised controlled trial
Primary purpose
Diagnosis
Masking
Blinded (masking used) (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients [age >18 yrs] admitted acutely under the care of a General Medicine team with dyspnoea and suspected volume overload will be selected by the study team.

Exclusion criteria

1) Patients who cannot be echoed within 24 hours of arriving in the Emergency Department 2) Patients unable or unwilling to provide fully informed consent

Outcome results

None listed

Source: ANZCTR · Data processed: May 16, 2026