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Effects of neck muscle vibration on brain activity and motor learning in healthy young adults

Vibration-induced modulation of spinal and cerebellar activity during motor learning in healthy adults

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12626000425392
Enrollment
36
Registered
2026-04-07
Start date
2024-09-16
Completion date
2025-11-03
Last updated
2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This experimental study examines how experimentally induced neck muscle vibration influences sensorimotor processing and motor learning in healthy adults. Participants are randomly allocated to one of three groups: 80 Hz vibration, 100 Hz vibration, or sham vibration (devices attached but not activated). Somatosensory evoked potentials are recorded using EEG following median nerve stimulation, and motor performance is assessed using a hand-grip force matching task. The intervention is applied once during a single laboratory session, with additional assessment of motor performance retention at 24 hours. The procedures are non-invasive and considered minimal risk. It is hypothesised that neck muscle vibration will alter somatosensory processing and motor performance compared to the control condition.

Interventions

The intervention will consist of experimentally induced, high-frequency, low-amplitude mechanical vibration applied to cervical muscles to transiently alter proprioceptive afferent input. Vibration will be delivered using portable mechanical vibration devices affixed to the skin over the right sternocleidomastoid muscle and left cervical extensor muscles using Hypafix tape. Participants will be randomly assigned to one of two active intervention groups: 80 Hz vibration or 100 Hz vibration. In th

The intervention will consist of experimentally induced, high-frequency, low-amplitude mechanical vibration applied to cervical muscles to transiently alter proprioceptive afferent input. Vibration will be delivered using portable mechanical vibration devices affixed to the skin over the right sternocleidomastoid muscle and left cervical extensor muscles using Hypafix tape. Participants will be randomly assigned to one of two active intervention groups: 80 Hz vibration or 100 Hz vibration. In the vibration conditions, mechanical vibration will be applied at the assigned frequency (80 Hz or 100 Hz) with an amplitude of less than 1 mm for a single continuous period of 10 minutes. The intervention will be delivered once during a single laboratory visit following baseline assessments. Participants will return to the laboratory 24 hours later for follow-up assessment of motor performance retention only. No vibration or comparator will be done on the retention day. The intervention will be delivered face-to-face on an individual basis in a controlled laboratory environment at a university research facility by trained research personnel with experience in neuromuscular and neurophysiological experimental protocols. Intervention fidelity will be ensured through the use of identical vibration devices and standardized placement procedures across participants. Adherence will be ensured through direct supervision by research staff, and completion of the full 10-minute stimulation period will be confirmed for all participants.

Sponsors

Prof. Bernadette Murphy - Ontario Tech University
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
17 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

Participants must be males and females aged 17 – 30, who are attending Ontario Tech University. All participants are required to be healthy and are to be free from chronic or recurrent neck, shoulder, or back pain. All participants will be screened for these inclusion and exclusion criteria using the chronic pain grade scale questionnaire and must have a score of less than 1 to be eligible. Right-handed individuals will be tested due to known differences in cortical excitability and sensorimotor processing between dominant and non-dominant limbs. Participants who score > +40 on the Edinburgh Handedness Inventory (Deemed right-handed) will be included in this study. Participants that are deemed ambidextrous, but have a strong inclination for right-hand dominance will also be included in the study.

Exclusion criteria

Left-handed participants will be excluded from the study (i.e. < -40 on Edinburgh Handedness Inventory). Participants cannot have any neurological or neuromuscular conditions that are known to impact neural function and/or neural processing (e.g. recurrent or chronic neck pain, multiple sclerosis, stroke, Parkinson’s etc.). All participants will be screened for these inclusion and exclusion criteria using a safety screening checklist.

Outcome results

None listed

Source: ANZCTR · Data processed: Apr 17, 2026