None listed
Conditions
Brief summary
The human nervous system exhibits neuroplastic adaptations in response to strength training, which enhance muscle force production. Neuroplasticity refers to the ability of the neuromuscular system to modify its function in response to physical activity, often involving reorganisation within the primary motor cortex that controls movement. Strength training has been shown to induce such plastic changes; however, limited evidence exists regarding how training affects the neural pathways connecting the neuromuscular system and skeletal muscle. Although the corticospinal pathway has been extensively studied in motor control and is considered one of the main sites of neural adaptation following resistance training, the role of other descending motor pathways, such as the reticulospinal pathway, remains largely unexplored in humans. It is also unclear whether strength training can modify the function of this pathway. Therefore, this project will investigate the effects of strength training on the modulation of neural systems, particularly the corticospinal and reticulospinal pathways, as well as motor unit behaviour, using non-invasive neurophysiological techniques. This research will provide new insights into neural adaptations and their contribution to training-induced increases in force output.
Interventions
Participants will complete a 4-week supervised resistance training program post randomisation targeting the elbow flexor muscles. The training will be performed three times per week, with each session lasting approximately 30 minutes. The exercise used in the program will be the biceps curl. Participants will perform the exercise at an intensity of approximately 85% of their one-repetition maximum (1RM). Each training session will consist of four sets of 6–8 repetitions, with all sessions conduc
Participants will complete a 4-week supervised resistance training program post randomisation targeting the elbow flexor muscles. The training will be performed three times per week, with each session lasting approximately 30 minutes. The exercise used in the program will be the biceps curl. Participants will perform the exercise at an intensity of approximately 85% of their one-repetition maximum (1RM). Each training session will consist of four sets of 6–8 repetitions, with all sessions conducted under the supervision of the research team to ensure correct technique and adherence to the training protocol.
Sponsors
Monash University
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Educational / counselling / training
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Healthy volunteers
Yes
Inclusion criteria
Healthy adults eligible for transcranial magnetic stimulation (TMS) and resistance training intervention. No neurological or musculoskeletal disorders
Exclusion criteria
Neurological disorders (e.g., epilepsy, stroke, Parkinson’s disease) Implanted metal devices or pacemakers Current CNS medications History of seizures or migraine History of resistance training
Outcome results
None listed