None listed
Conditions
Brief summary
This study evaluates the outcome of incision and drainage of subcutaneous abscesses in children with and without the use of antibiotics. Children will receive either postoperative antibiotics or wound care alone after the procedure. The study aims to determine whether antibiotics improve recovery or reduce recurrence after incision and drainage
Interventions
Children aged 01 years to 12 years presenting with a subcutaneous abscess measuring more than 2 cm and less than 6 cm in diameter will undergo incision and drainage (I&D) under aseptic conditions in the minor operation theater.
The procedure will take approximately 20–30 minutes.
After incision and drainage, children in the intervention group will be prescribed oral amoxicillin–clavulanic acid at a dose of 30–50 mg/kg/day, divided into three doses (three times daily [TDS]), for a duration of 5 d
Children aged 01 years to 12 years presenting with a subcutaneous abscess measuring more than 2 cm and less than 6 cm in diameter will undergo incision and drainage (I&D) under aseptic conditions in the minor operation theater. The procedure will take approximately 20–30 minutes. After incision and drainage, children in the intervention group will be prescribed oral amoxicillin–clavulanic acid at a dose of 30–50 mg/kg/day, divided into three doses (three times daily [TDS]), for a duration of 5 days. Daily wound dressing will be performed by a registered nurse. Adherence to the intervention will be assessed through review of medical records and followup visits
Sponsors
National Institute of child Health Karachi
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Educational / counselling / training
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
1 Years to 12 Years
Healthy volunteers
No
Inclusion criteria
1.Age 1–12 years. 2.Male or female. 3.Presenting with a subcutaneous abscess meeting the operational definition: localized, fluctuant swelling 2–6 cm in greatest dimension with overlying erythema and warmth. Caregiver able and willing to provide informed consent and to attend follow-up on day 7.
Exclusion criteria
1.Children with a recent history of antibiotic intake (within the last 7 days), verified through medical records or caregiver report. 2.Known cases of congenital immunodeficiency disorders, confirmed from medical records. 3.Presence of any systemic illness such as diabetes mellitus, chronic renal disease, congenital heart disease, or malignancy 4.Children with severe malnutrition, as per WHO criteria (weight-for-height Z-score = -3 SD or presence of nutritional edema). 5.Presence of multiple abscesses on the body. 6.Known hypersensitivity or allergy to co-amoxiclav. 7..Abscess size less than 2 cm or greater than 6 cm in greatest dimension. 8.Abscess located in perineal, perianal, or paronychial regions.
Outcome results
None listed