None listed
Conditions
Brief summary
The primary objective of our study is to assess the effect of adding magnesium sulfate to the local anesthetic levobupivacaine in the rectus sheath block on the duration of the blockade. We hypothesize that the addition of magnesium sulfate will increase the duration of the block. The purpose of our research is to determine the quality and duration of postoperative analgesia after bilateral rectus sheath block (RSB) in colorectal surgeries with a midline laparotomy approach, as well as the total postoperative opioid consumption over 24 hours.
Interventions
After induction into general anesthesia, an experienced anesthesiologist will perform a bilateral rectus sheath block under ultrasound guidance. The rectus sheath block will include 30 ml of 0.25% Levobupivacaine with an addition of 500mg magnesium sulfate in total, with half the dose applied to one side and the other half to the opposite side.
Adherence to intervention will be assessed through review of operative medical notes
Sponsors
University Hospital Sestre Milosrdnice
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Consenting patients over the age of 18 undergoing elective colorectal surgery.
Exclusion criteria
Exclusion criteria are: patients undergoing emergency surgery, ASA greater than 3, reoperation, history of opioid abuse, chronic pain syndromes, infection at the site where the block is performed, history of allergy to local anesthetics, coagulation disorders and patient withdrawing consent.
Outcome results
None listed