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A retrospective study of the outcome of ceftriaxone vs cefazolin for the treatment of paediatric cellulitis in patients admitted to Hospital in the Home.

A retrospective study of the efficacy of ceftriaxone vs cefazolin for the treatment of paediatric cellulitis in patients admitted to Hospital in the Home.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12626000297325
Enrollment
384
Registered
2026-03-09
Start date
2024-11-15
Completion date
2025-09-07
Last updated
2026-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

To compare the outcome of daily intermittent intravenous dosing of ceftriaxone verses continuous intravenous infusion of cefazolin by looking at treatment duration in patients admitted with cellulitis to the CHQ at Home’s Hospital in the Home program from 1st of January 2020 to 30th of June 2024.

Interventions

To compare the outcome of daily intermittent intravenous dosing of ceftriaxone verses continuous intravenous infusion of cefazolin by looking at treatment duration in patients admitted with cellulitis to the Cildren's Health Queensland (CHQ) Home’s Hospital in the Home program from 1st of January 2020 to 30th of June 2024. The retrospective study involve individual chart review to determine the duration on IV antibiotics .

Sponsors

Queensland Children's Hospital
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
3 Months to 17 Years
Healthy volunteers
No

Inclusion criteria

All children with a cellulitis diagnosis admitted to the CHQ at home HITH program between 1 January 2020 and 30 June 2024 were identified through the hospital informatic system. Only patients who received either ceftriaxone or cefazolin were included in audit.

Exclusion criteria

Children with underlying complex co-morbidities, such as immunodeficiency (including patients on chemotherapy, corticosteroids, or biologic agents) or significant renal or liver disease were excluded • Complex cellulitis (e.g., associated with vascular malformation, multiple concurrent soft tissue infections, infection secondary to an implanted device or cellulitis with complex abscess requiring surgical drainage in theatre) • Postoperative or radiotherapy complication • Diagnosed or suspicion of orbital cellulitis • Cellulitis secondary to infected varicella and HSV • Non cellulitis soft tissue infection

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 20, 2026