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PRECISION-SAH: A multi-centre prospective observational cohort study of patients with aneurysmal subarachnoid haemorrhage

PRECISION-SAH: A multi-centre prospective observational cohort study of clinical outcomes in patients with aneurysmal subarachnoid haemorrhage

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12626000222347
Enrollment
200
Registered
2026-02-23
Start date
2026-03-23
Completion date
2027-10-01
Last updated
2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

PRECISION-SAH is a national research project focused on improving care for patients admitted to ICUs with a serious type of brain bleed called aneurysmal subarachnoid haemorrhage (aSAH). Although medical care for this condition has improved over time, many patients still face serious risks, including brain damage and death. PRECISION-SAH will collect detailed clinical information from patients at hospitals around Australia. The goal is to understand how different hospitals manage care, identify which treatments work best, and find early warning signs of DCI.

Interventions

This is an observational study, there is no intervention. The study will collect data from patients who are diagnosed with an aneurysmal subarachnoid haemorrhage (aSAH), a serious type of brain bleed which is associated with high mortality and long-term disability. The study will collect data about patient demographics, medical history, initial presentation with aSAH (clinical presentation, SAH symptoms and grading), daily ICU data (e.g. physical and neurological assessments, vital signs, imagin

This is an observational study, there is no intervention. The study will collect data from patients who are diagnosed with an aneurysmal subarachnoid haemorrhage (aSAH), a serious type of brain bleed which is associated with high mortality and long-term disability. The study will collect data about patient demographics, medical history, initial presentation with aSAH (clinical presentation, SAH symptoms and grading), daily ICU data (e.g. physical and neurological assessments, vital signs, imaging), management of the patient and neurological outcome after the event. The required data during hospitalisation are already being collected during routine clinical care. Patients and/or their next of kin will be asked to complete a follow-up telephone interview 6-months post-enrolment. This will take approximately 30 minutes and include 3 assessments (modified Rankin scale, Subarachnoid Haemorrhage Outcome Tool and EQ-5D-5L). The overall duration of observation is 6 months.

Sponsors

Monash University
Lead SponsorUniversity

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

- Clinical diagnosis of aneurysmal subarachnoid haemorrhage (aSAH) - Admitted to the ICU with or without invasive neuromonitoring as per the treating clinical team

Exclusion criteria

- Admission to the ICU solely for the purposes of palliative care or confirmation of organ donation - Advanced care directive or previously stated wish not to be included in research activities

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 14, 2026