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A better bypass: using ultrasounds of thigh muscles to predict complications for patients after cardiac surgery

A better bypass: using ultrasounds of thigh muscles to predict complications for patients after cardiac surgery

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12626000071325
Enrollment
190
Registered
2026-01-20
Start date
2026-02-02
Completion date
2026-08-01
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Post-operative pulmonary complications occur in approximately 10–25% of patients following cardiac surgery, contributing to delayed mobilisation, prolonged ICU and hospital length of stay, and poorer recovery outcomes. Early identification of patients at higher risk of complications and objective monitoring of deconditioning during recovery remain unmet clinical needs. Skeletal muscle status reflects physiological reserve and vulnerability to critical illness. Emerging evidence suggests that rectus femoris muscle cross-sectional area and echogenicity, measured using real-time ultrasound, may predict adverse outcomes in hospitalised populations. Ultrasound is non-invasive, low-cost, portable, and increasingly feasible for use by allied health clinicians in acute and ICU settings. This study evaluates whether cross sectional area of the rectus femoris muscle can be reliably implemented in cardiac surgery pathways and whether these measures predict clinically meaningful outcomes.

Interventions

Patients who are admitted to Calvary Adelaide Hospital to undergo Coronary Artery Bypass Graft or Mitral Valve replacement or Atrial Valve replacement performed via sternotomy are invited to participate in the study. Once a patient consents to the study, they will have a pre-surgery assessment of their routine Physiotherapy pre-operative assessment and in addition an assessment of the quadriceps muscle using the Real Time Ultrasound Machine. The Pre-operative physiotherapy assessment involves a

Patients who are admitted to Calvary Adelaide Hospital to undergo Coronary Artery Bypass Graft or Mitral Valve replacement or Atrial Valve replacement performed via sternotomy are invited to participate in the study. Once a patient consents to the study, they will have a pre-surgery assessment of their routine Physiotherapy pre-operative assessment and in addition an assessment of the quadriceps muscle using the Real Time Ultrasound Machine. The Pre-operative physiotherapy assessment involves a subjective examination asking about any cardiorespiratory symptoms, their exercise tolerance, falls history, social history and current goals for discharge. In addition patients undergo an objective assessment, assessing their lungs via auscultation and palpation, along with a mobility assessment and ability to transfer between positions in bed. Patients are also taught sternal precautions post operatively and how to mobilise in and out of bed following precautions. The real time ultrasound measure of the quadriceps muscle will occur daily until discharge. In addition medical records will be access to record details regarding demographics including sex, age, location, co-morbidities and current medications. In addition they will be asked questions on a likert scale to determine acceptability and feasibility of the study. All assessments will be done by Physiotherapists in the hospital who have been trained by a registered sonographer only once they have met an acceptable level of inter and intra rater reliability in the measurement of quadriceps muscles.

Sponsors

Health Translation South Australia
Lead SponsorGovernment body

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Adults undergoing surgery performed via sternotomy who are able to give informed consent. For example, procedures include: • Coronary artery bypass grafting (CABG), and/or • Aortic valve replacement (AVR), and/or • Mitral valve repair or replacement (MVR)

Exclusion criteria

• Inability to obtain ultrasound images (e.g. limb amputation) • Contraindications to positioning • Inability to provide informed consent

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026