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Efficacy of potassium nitrate and fluoride varnish in reducing tooth hypersensitivity.

Comparison of effect of potassium nitrate and fluoride varnish in reducing post vital tooth preparation hypersensitivity: A randomized controlled trial

Status
Not yet recruiting
Phases
Phase 4
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12626000017325
Enrollment
58
Registered
2026-01-07
Start date
2026-01-12
Completion date
2026-02-27
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study compares the effectiveness of potassium nitrate varnish and fluoride varnish in reducing tooth sensitivity that occurs after tooth preparation for crowns or bridges. Such sensitivity, known as dentinal hypersensitivity, is a common issue after dental procedures involving exposed dentin. Participants will receive one of the two treatments, and their level of discomfort will be monitored over time. We hypothesize that potassium nitrate varnish is more effective than fluoride varnish in reducing post-preparation tooth sensitivity.

Interventions

Duration of the intervention would be 2 hours which would be applied to the teeth after tooth cutting/preparation. The concentration of potassium nitrate would be 6% which will be administered by the dentist. The strategies used to monitor adherence to the intervention if applicable would be medical records .

Sponsors

Dr. Khadija Ayaz- Khyber College of Dentistry Peshawar
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject)

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

1. Patients with vital tooth in need of fixed prosthesis restorations. 2.The selected teeth should not be adjacent. 3. Healthy patients who do not require the use of prophylactic antibiotics or complementary steroids.

Exclusion criteria

1. Patients allergic to desensitizers. 2. Non vital/ endodontically treated tooth. 3. Periodontal disease. 4. Carious tooth 5. Hypersensitivity of the teeth. 6. Use of antihistamine, anti inflammatory, analgesic and opioid drus.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026