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Nurse-led nutritional support for managing chemotherapy-induced diarrhoea and constipation: A pilot trial

A pilot trial of a co-designed nurse-led nutritional support intervention for chemotherapy-induced diarrhoea and constipation among cancer patients in Vietnam

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12626000016336
Acronym
Nutri-CICID Pilot
Enrollment
80
Registered
2026-01-07
Start date
2024-03-25
Completion date
2024-06-28
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study aimed to find out whether a nurse-led nutritional support program is practical and acceptable for helping patients manage diarrhoea and constipation caused by chemotherapy. The program was developed together with patients and healthcare professionals and includes personalised dietary guidance, a self-management booklet, and weekly telephone support. The primary purpose of this pilot study was to determine whether the program can be delivered successfully, whether patients are willing to participate and follow the recommendations, and whether the study procedures are suitable for a future larger clinical trial.

Interventions

A co-designed, nurse-led nutritional support program was delivered over 12 weeks to support patients in managing chemotherapy-induced diarrhoea and constipation (CID/CIC). The intervention comprised face-to-face education, a culturally tailored educational booklet, weekly telephone follow-up, and the promotion of self-management strategies. The face-to-face education session was delivered by a research nurse and focused on assessing the severity of CID/CIC, reviewing participants’ existing phar

A co-designed, nurse-led nutritional support program was delivered over 12 weeks to support patients in managing chemotherapy-induced diarrhoea and constipation (CID/CIC). The intervention comprised face-to-face education, a culturally tailored educational booklet, weekly telephone follow-up, and the promotion of self-management strategies. The face-to-face education session was delivered by a research nurse and focused on assessing the severity of CID/CIC, reviewing participants’ existing pharmacological and non-pharmacological self-management approaches, and evaluating dietary and lifestyle practices. Personalised, symptom-based dietary counselling was provided using a culturally tailored booklet developed specifically for this study. Participants were also trained in the “I Love U” abdominal massage technique through in-person demonstration and received guidance on bowel symptom monitoring and effective communication with healthcare professionals. Each participant received one initial face-to-face education session at baseline, lasting approximately 30–45 minutes. This was followed by weekly nurse-led telephone follow-up calls over the subsequent 12 weeks. During these calls, bowel symptoms were reviewed, key dietary messages were reinforced, patient questions or challenges were addressed, and dietary advice was adjusted as needed in response to symptom changes. Adherence to the intervention was assessed by documenting attendance at the initial face-to-face education session and completion of the scheduled weekly telephone follow-up contacts. Self-management strategies were introduced during the face-to-face education session and reinforced throughout follow-up. These strategies included patient-led dietary modifications, hydration practices, abdominal massage, and bowel symptom monitoring using a diary.

Sponsors

Queensland University of Technology
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Primary purpose
Educational / counselling / training

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

• Over 18 years old • Being diagnosed with cancer at any stage. • Have finished their second chemotherapy cycle. • Report previous CID/CIC in their previous last cycle. • Having normal ranges of hematology and biochemistry lab values • Eastern Cooperative Oncology Group (ECOG) performance status < 2 indicating that patients can perform all self-care activities (see Section 5.3.6). • Expected prognosis of at least 12 months (determined by the referring oncologist) • Able to communicate in Vietnamese. • Consent to participate in the study.

Exclusion criteria

• Inability to complete the survey due to literacy level or communication impairment. • Had chronic constipation or diarrhoea due to reasons other than chemotherapy. • Patients with any chronic digestive disorders 3 months prior to the diagnosis of cancer • Patients with emesis-inducing diseases such as hypertension, liver, and renal failure • Involved in other clinical trials. • Patients whose clinical treatment team deem are not a suitable candidate to participate in the study (e.g., not well enough). • Potential participants would be excluded if a member of the treatment team believes that (1) participation may distress the potential participant (or family member) and/or (2) a patient does not have the cognitive or communicative capacity to participate.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026