None listed
Conditions
Brief summary
This randomized controlled trial aims to evaluate the effects of a 12-week moderate-intensity aerobic exercise program on high-sensitivity C-reactive protein (hs-CRP) levels and mental health indicators, specifically anxiety and depression, in obese male adults. A total of 60 participants from Government Post Graduate College Peshawar will be randomly assigned to intervention and control groups. Pre- and post-intervention assessments will include hs-CRP blood tests and the Hospital Anxiety and Depression Scale (HADS). The study seeks to determine whether aerobic exercise can reduce systemic inflammation and improve mental health, offering a non-pharmacological approach to managing obesity-related health concerns. Findings may guide future interventions and public health policies targeting both physical and psychological aspects of obesity in similar populations.
Interventions
The intervention exposure in this study involves a structured, moderate-intensity aerobic exercise program designed specifically for the experimental group (Group A). Under the kind supervision of a physical trainer and local health professional, 30 Participants will engage in aerobic sessions for a duration of 12 weeks, with a frequency of five days per week. Each session will last approximately 55 minutes and will follow a consistent format aimed at reducing inflammation and improving mental health indicators such as depression and anxiety. The session structure includes a 5-minute warm-up, followed by 5 minutes of stretching exercises to prepare the muscles and joints for physical activity. This is followed by 10 minutes of jogging, 10 minutes of brisk walking, and 10 minutes of running, all performed at a moderate intensity. The session concludes with a 10-minute cool-down period to help the body return to its resting state and reduce physical strain. A 1-minute rest interval is between each activity to allow for adequate recovery and to ensure safety. This protocol, adapted from Kamal and Ragy (2012), is designed to reduce adipose tissue, lower pro-inflammatory markers such as CRP, and contribute to improved mental health outcomes, particularly by alleviating symptoms of depression and anxiety in obese adults. The intervention will be carried out in a college playground to maintain consistency, encourage adherence, and ensure participant safety throughout the study period.
Sponsors
Study design
Eligibility
Inclusion criteria
“Participants will be included if they had a body mass index (BMI) greater than or equal to 30 kg/m², classifying them as obese according to WHO criteria.”
Exclusion criteria
Presence of chronic illnesses (e.g., cardiovascular, respiratory, hepatic, or musculoskeletal disorders). Diagnosed with severe psychiatric conditions or currently under psychiatric treatment. Use of medications that affect inflammation or mental health (e.g., anti-inflammatory drugs, antidepressants). Current engagement in structured exercise programs or recent acute illness/infection (within the past 4 weeks).