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Physiotherapy Airway Clearance in the Education Setting (PACES)

Physiotherapy Airway Clearance in the Education Setting (PACES) for the management of children with bronchiectasis aged 5 to 12 years living in Counties Manukau.

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12625001334493
Acronym
PACES
Enrollment
48
Registered
2025-12-01
Start date
2026-01-26
Completion date
2027-10-29
Last updated
2026-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study will test whether the PACES (Physiotherapy Airway Clearance in the Education Setting) programme can improve health outcomes for children aged 5–12 years with bronchiectasis in Counties Manukau. Children will be randomly assigned to receive either PACES plus standard care or standard care alone, with each child remaining in their assigned group for 12 months. The PACES programme provides supervised airway clearance at school using techniques and devices to help clear mucus from the lungs. The primary outcomes are cough-specific quality of life and cardiorespiratory fitness. Secondary outcomes include hospital visits, antibiotic use, and parent-reported quality of life.

Interventions

Home-based airway clearance (Standard Care): Participants will complete daily airway clearance at home using a combination of airway clearance devices and breathing techniques to support sputum clearance while maintaining infection control. Sessions last 15–30 minutes, once per day, seven days per week, and are supervised by caregivers. Adherence is recorded in a daily diary and reviewed by the lead researcher at baseline, 6-month, and 12-month visits. School-based airway clearance (PACES inter

Home-based airway clearance (Standard Care): Participants will complete daily airway clearance at home using a combination of airway clearance devices and breathing techniques to support sputum clearance while maintaining infection control. Sessions last 15–30 minutes, once per day, seven days per week, and are supervised by caregivers. Adherence is recorded in a daily diary and reviewed by the lead researcher at baseline, 6-month, and 12-month visits. School-based airway clearance (PACES intervention): Participants in the PACES programme complete daily supervised airway clearance sessions at school, using a combination of airway clearance devices and breathing techniques. Sessions last 10–15 minutes, once per school day, and are delivered one-to-one with a trained staff member. Adherence is recorded in a daily diary by staff and reviewed by the lead researcher during termly visits and email check-ins. Airway clearance techniques are tailored to each child’s clinical needs based on bronchiectasis best management recommendations. Devices may include positive expiratory pressure devices (e.g., TheraPEP, PariPEP, bubblePEP), oscillating devices (e.g., Aerobika, Acapella), or high-frequency chest wall oscillation where indicated. Breathing techniques may include diaphragmatic breathing, thoracic expansion exercises, huffing, and coughing. Initial staff training (PACES intervention): Prior to programme commencement, nominated school staff receive a single 60–90 minute face-to-face training session from the lead researcher. Training includes education on bronchiectasis, practical airway clearance instruction, infection control procedures, and symptom monitoring, with a competency check completed with the child participant. Staff are provided with equipment, action plans, and contact details for the lead researcher and clinic.

Sponsors

Aotearoa Clinical Trials Trust (ACTT)
Lead SponsorOther

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Investigator)

Eligibility

Sex/Gender
All
Age
5 Years to 13 Years
Healthy volunteers
No

Inclusion criteria

Children aged 5–12 years, residing and attending school in Counties Manukau, with adequate English for written informed consent (child and guardian), confirmed non-cystic fibrosis bronchiectasis on HRCT, and moderate to severe disease by meeting at least three of the following criteria: Three or more lobes affected with bronchiectasis, cystic bronchiectasis, or persistent lobar collapse on HRCT; FEV1 Z-score less than or equal to -1.65; three or more antibiotic courses in past 12 months; one or more hospital admission in past 24 months; current or prior (previous 24 months) azithromycin prescription; port-a-cath in situ; positive Pseudomonas aeruginosa culture). Must be under care of a physiotherapist with a prescribed airway clearance programme (e.g., TheraPEP, Acapella, Aerobika, PariPEP, autogenic drainage, or oscillating vest).

Exclusion criteria

Children are excluded if they currently receive school-based airway clearance physiotherapy as part of another service, have severe physical or cognitive impairments (e.g., global developmental delay, cerebral palsy, chromosomal syndromes) that limit participation or outcome testing, or have another primary respiratory disease where bronchiectasis is secondary (e.g., asthma).

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 19, 2026