None listed
Conditions
Brief summary
The PaCNOD Pilot study aims to test the feasibility of conducting a large-scale trial of CT scans in some people with recently diagnosed diabetes to determine if it leads to diagnosis of pancreatic cancer at an earlier stage. Who is it for? You may be eligible for this study if you are aged 55 years or older with a recent diagnosis of diabetes, and no self-reported history of pancreatic cancer or pancreatic resection. Study details All participants will be asked to complete a survey about their health history. A subset of participants who are deemed to be at higher than average risk of pancreatic cancer will be invited to have a CT scan of their pancreas. Data will be collected on the feasibility of this investigative workflow, including the involvement of primary care doctors and private radiology providers. It is hoped that findings from this study will help researchers understand the utility of CT scans in early diagnosis of pancreatic cancer in this population.
Interventions
A subset of participants will be invited to undergo a pancreatic protocol contrast CT scan. Participants will be referred to a private imaging provider with whom QIMR Berghofer has an agreement. The volume/dose of a contrast dye will be injected into a blood vessel. to facilitate the CT scans according to the standard protocol used by a service provider. It will be administered by a radiographer. The approximate duration of the contrast CT scan is 30-60 minutes. Most participants will be asked
A subset of participants will be invited to undergo a pancreatic protocol contrast CT scan. Participants will be referred to a private imaging provider with whom QIMR Berghofer has an agreement. The volume/dose of a contrast dye will be injected into a blood vessel. to facilitate the CT scans according to the standard protocol used by a service provider. It will be administered by a radiographer. The approximate duration of the contrast CT scan is 30-60 minutes. Most participants will be asked to complete a contrast CT scan participant feedback survey designed specifically for this study. The radiology report will be returned to QIMR Berghofer.
Sponsors
QIMR Berghofer
Study design
Allocation
Non-randomised trial
Primary purpose
Diagnosis
Eligibility
Sex/Gender
All
Age
55 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Age 55 years or older; 2. No self-reported history of pancreatic cancer; 3. No self-reported history of a partial or total pancreatic resection; 4. Able to provide consent (i.e., no cognitive impairment); 5. Has a Medicare card; 6. Has a phone; and 7. Has access to an electronic device suitable for survey completion. Some participants, who have indicators of being at higher than average risk of pancreatic cancer, will be invited to have a CT scan. They must have none of the following: 1. Cognitive impairment such that the participant may not understand the risks associated with a contrast CT scan; 2. Kidney disease/injury/ history of surgery involving the kidneys; 3. eGFR <60 mL/min/1.73m2 at a previous blood test; 4. Uncontrolled hyperthyroidism; 5. Previous allergic reaction to contrast dye; 6. Known anaphylaxis to any allergen; 7. Currently receiving active cancer treatment (e.g., systemic therapy, radiotherapy, surgery within the past 3 months, or awaiting surgery) 8. Currently undergoing diagnostic investigations including imaging of the abdomen/pelvis.
Exclusion criteria
NA
Outcome results
None listed