Comparing the therapeutic efficacy of oral minoxidil and oral finasteride in androgenic alopecia in males

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12625001306404

Enrollment

Registered

2025-11-24

Start date

2025-11-03

Completion date

2026-05-03

Last updated

2025-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

A comparative study of oral minoxidil 1.25 mg daily with oral finasteride 1 mg on alternate days in androgenic alopecia, will be conducted at Dermatology out-patient department, PNS Shifa hospital Karachi after fulfilling the inclusion and exclusion criteria. After the informed written consent and permission from hospital’s ethics review committee, 62 patients will be divided in Group A & B. Patients in both the groups will receive treatment for 6 months and data from patient will be collected through a proforma on first visit and follow-ups', etc. The study aims to compare the effectiveness of two medications, oral minoxidil and oral finasteride, in treating androgenic alopecia (male pattern baldness).

Interventions

Patients will be randomized into two groups (Group A&B). Group A will receive oral minoxidil 1.25mg daily ( Tab Minoxidil 2.5mg will be split into 2 halves and each half will be taken daily). All the patients will be provided with the same brand of medicine to minimize brand bias. All patients will asked to bring used tablet pack at every visit ( 1 visit per month) for adherence purposes.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

Male

Age

18 Years to 45 Years

Healthy volunteers

Inclusion criteria

1. Male 2. Age 18-45 years 3. Androgenetic alopecia with Hamilton-Norwood scale - Stage I - IV 4. Patients without any known systemic illness / psychiatric illness 5. Patients not taking any treatment for last 3 months

Exclusion criteria

1. Patients on any systemic / immuno-suppressive therapy 2. Cases with any hepatic or renal failure 3. Patients who are known to be hypersensitive to minoxidil or finasteride 4. Patients using other therapies for restoring hair or taking any other systemic medications (like steroids, cytotoxic drugs or others) 5. Patients with androgenic alopecia associated with other dermatological conditions.

Outcome results