Skip to content

Comparison of the effects of two differents blocks on postoperative analgesia in laparoscopic cholecystectomy

Comparison of the effects of modified thoracoabdominal nerve block through perichondrial approach and erector spinae plane block on postoperative analgesia in laparoscopic cholecystectomy

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12625001305415
Enrollment
40
Registered
2025-11-24
Start date
2022-12-13
Completion date
2023-05-01
Last updated
2025-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Although laparoscopic cholecystectomy (LC) is an invasive surgical technique with fewer postoperative complications than open cholecystectomy, postoperative pain can occur. Inadequate pain management can lead to thromboembolic, pulmonary, and cardiological complications, prolonged mobilization and rehabilitation, and increased hospital stays and costs. Furthermore, inadequately treated acute pain can lead to chronic pain, negatively impacting patient life. M-TAPA and ESPB are block methods used for postoperative analgesia in laparoscopic cholecystectomy. This study aimed to compare the effectiveness of these two blocks on postoperative analgesia.

Interventions

Modified thoracoabdominal nerves block through perichondrial approach: Modified thoracoabdominal nerves block through perichondrial approach (m-tapa) is a type of block used for postoperative analgesia in various abdominal surgeries, reported to provide abdominal analgesia by blocking both the anterior and lateral cutaneous branches of the thoracabdominal nerves by applying local anesthesia to the underside of the costochondral chondrium at the 9th and 10th costal levels. Before surgery began, a

Modified thoracoabdominal nerves block through perichondrial approach: Modified thoracoabdominal nerves block through perichondrial approach (m-tapa) is a type of block used for postoperative analgesia in various abdominal surgeries, reported to provide abdominal analgesia by blocking both the anterior and lateral cutaneous branches of the thoracabdominal nerves by applying local anesthesia to the underside of the costochondral chondrium at the 9th and 10th costal levels. Before surgery began, after ensuring appropriate sterilization, a linear ultrasonography (USG) probe was aseptically inserted into the costochondral angle at the level of the 9th and 10th ribs in the sagittal plane. The transverse abdominis muscle, internal oblique muscle, and external oblique muscle were visualized. The probe was then angled deeply to visualize the underside of the chondrium. Using the in-plane technique, an 80 mm 22-gauge peripheral blocking needle (Stimuplex®, B Braun, Melsungen, Germany) was guided caudally to the cephalad plane, advancing the needle tip to the underside of the chondrium. After confirming the absence of vascular access by aspiration, an M-TAPA block was performed by injecting 20 ml of 0.25% bupivacaine (Buvasin vial, Vem, Istanbul, Türkiye). All M-tapas were performed by an anesthesiologist who has been working for at least 5 years. Anesthesia was maintained with 50% O2 + 50% air with 6% desflurane (Suprane®, Baxter, USA), fentanyl, and rocuronium titration. Any complications related to the block were recorded during intraoperative follow-up. At the end of surgery, patients were antagonized with 2 mg/kg sugammadex (Bridion®, Sanofi, Tekirdag, Turkey) after the inhaled agent was removed and the muscle relaxant effect was antagonized. After extubation, they were taken to the postoperative recovery room. Arrival time to the recovery room was considered 0. The first VAS assessment of patients who underwent M-TAPA was performed here.Any side effects or complications such as hypotension, vascular puncture, paresthesia, and local anesthetic toxicity that developed during block application were documented. Patients who met the recovery criteria were followed up in the general surgery clinic. Demographic data obtained from postoperative recovery room and ward follow-ups of all patients, postoperative rest and dynamic VAS scores at 0, 2, 4, 6, 8, 12, and 24 hours, and patient satisfaction at 24 hours were reviewed and recorded. The time of first analgesic use at 24 hours postoperatively was recorded on the case report form.

Sponsors

Afyonkarahisar Health Science University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

The patients aged between 18 and 70, classified as American Society of Anesthesiologists (ASA) I-III, who were scheduled for elective cholecystectomy.

Exclusion criteria

Patients outside the age range of 18-70, those with ASA scores above III, local or systemic infections,mental or psiychiatric disorders serious arrhythmias, and cardiac, hepatic, or renal failure were excluded from the study.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026