None listed
Conditions
Brief summary
This study aims to find out which disinfecting solution works better for relieving pain after root canal treatment — Chlorhexidine or Sodium Hypochlorite. Both are commonly used during treatment to clean out infection inside the tooth. Some dentists are concerned that Sodium Hypochlorite, although effective, may cause irritation and pain. Chlorhexidine may be gentler but is not used as often on its own. This study will compare both solutions to see if Chlorhexidine is just as good or better at reducing pain after root canal treatment in patients with toothache and dental infection. Patients will be randomly assigned to one of the two groups, and their pain levels will be tracked over one week.
Interventions
Patients in the 2% Chlorhexidine (CHX) group will undergo standard root canal treatment under local anaesthesia using 2% lidocaine with 1:100,000 epinephrine. Rubber dam isolation will be applied, and an access cavity will be prepared. Mechanical instrumentation will be carried out using hand and rotary files, and the canals will be irrigated throughout the procedure with 2% chlorhexidine solution. After instrumentation, the canals will be dried with paper points, medicated with calcium hydroxid
Patients in the 2% Chlorhexidine (CHX) group will undergo standard root canal treatment under local anaesthesia using 2% lidocaine with 1:100,000 epinephrine. Rubber dam isolation will be applied, and an access cavity will be prepared. Mechanical instrumentation will be carried out using hand and rotary files, and the canals will be irrigated throughout the procedure with 2% chlorhexidine solution. After instrumentation, the canals will be dried with paper points, medicated with calcium hydroxide, and temporarily restored with Cavit. All treatment procedures will be performed by a qualified dentist in the Department of Operative and Endodontic Dentistry. This intervention will be completed in a single appointment lasting approximately 45–60 minutes. Patients will return after 7 days for evaluation. During preparation, up to 10 ml of 2% chlorhexidine solution will be used per tooth as the irrigant. All treatment will take place in the Operative and Endodontic Dentistry Department at Khyber College of Dentistry, Peshawar. To monitor adherence, details of treatment and irrigant use will be documented in the patient’s clinical record. Patients will receive a Visual Analogue Scale (VAS) diary to record postoperative pain at 24 hours, 48 hours, 3 days, and 7 days. Compliance will be assessed at the 7-day follow-up visit.
Sponsors
Khyber College of Dentistry
Study design
Allocation
Randomised controlled trial
Primary purpose
Treatment
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
Patients with a vital tooth diagnosed with symptomatic irreversible pulpitis and symptomatic apical periodontitis requiring root canal treatment. Tooth must have a single canal and fully formed apex. Patient reports severe preoperative pain (VAS score 7–10). Age 18 years or older. ASA I or ASA II physical status (no complicating systemic disease). Patient is willing to provide informed consent and comply with follow-up instructions.
Exclusion criteria
Patients under 18 years of age. Use of antibiotics within the last 2 weeks prior to treatment. Teeth that are non-restorable or have periodontal pockets greater than 3 mm. Teeth with calcified canals or complex root canal anatomy (e.g. multiple canals). Patients with serious systemic illness beyond ASA II classification. Patients unable or unwilling to give informed consent or comply with follow-up.
Outcome results
None listed