Skip to content

Body Composition assessment in morbidly obese bariatric surgery patients, a prospective longitudinal cohort study.

Body Composition assessment in morbidly obese bariatric surgery patients, a prospective longitudinal cohort study.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12625001233415
Enrollment
49
Registered
2025-11-06
Start date
2018-11-13
Completion date
2022-12-12
Last updated
2025-11-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study aims to measure how much muscle (fat-free mass) and fat patients lose in the months after metabolic weight loss surgery and whether simpler, non-invasive tools such as bioelectrical impedance spectroscopy (BIS) and ultrasound can accurately measure these body composition changes compared to the reference method (DEXA scan). We hypothesise that BIS and ultrasound will provide measurements of body fat and muscle that are close to those obtained from DXA scans, making them reliable and practical methods for tracking body composition changes after surgery. We also hypothesise that those that lose the greatest fat and least muscle will have better metabolic outcomes after surgery.

Interventions

Patients undergoing primary sleeve gastrectomy surgery (metabolic weight loss surgery) for obesity treatment in Melbourne, VIC at private and 1 public hospital, will undergo body composition analysis and functional assessments within 1 month prior to surgery and repeated again at 12 months post-operatively. DEXA scans, bioimpedance analysis and ultrasound measures of body composition will be performed at study visits by 1 study investigator. All other clinical data (weight, waist circumference,

Patients undergoing primary sleeve gastrectomy surgery (metabolic weight loss surgery) for obesity treatment in Melbourne, VIC at private and 1 public hospital, will undergo body composition analysis and functional assessments within 1 month prior to surgery and repeated again at 12 months post-operatively. DEXA scans, bioimpedance analysis and ultrasound measures of body composition will be performed at study visits by 1 study investigator. All other clinical data (weight, waist circumference, height, physical activity level, bloods) will either be collected on the day of study visit by the study investigator from the patient or their hospital files (no additional measurements outside of routine clinical care will be collected for the purpose of the study). The anticipated time needed to complete DEXA scan (30 mins), bioimpedance analysis (20 minutes) and ultrasound (20 minutes) measures of body composition is a total of 70 minutes per study visit. The DEXA scan will involve participants wearing light clothing, with metal such as jewellery removed, laying down on a bed while the scanner arm passes over their body, a non-invasive low dose x-ray scan is performed to produce a total body scan. For ultrasound measurements, participants are asked to wear loose clothing that allows easy access to thighs, upper arm and abdomen. They will be laying down on a hospital bed with their head elevated 30 degrees. The study investigator will then undertake a non-invasive ultrasound image protocol using a probe that uses sound waves to create real time images of body tissue at the upper arm, forearm, mid-thigh and umbilicus. Following the ultrasound, the participants will remain laying on the hospital bed and the study investigator will then apply 2 electrodes on participants right hand and 2 electrodes on participants right foot. 3 separate bioimpedance scans will be conducted 5 minutes apart. The bioimpedance scan involves a very low voltage electrical current that is applied to the body from the electrodes, to measure resistance and reactance of the body. All study visits will be located at Monash University Alfred Hospital campus in Melbourne, VIC.

Sponsors

The Alfred Hospital
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

- greater than or equal to 18 years of age on day of surgery. - BMI equal to or greater than 35kg/m2 on day of surgery. - Waitlisted for bariatric surgery by surgeons (public and private hospitals) - able to provide written consent in English

Exclusion criteria

-Not eligible for surgery -Participants with pacemaker or other electronic implantable device -Known to be pregnant -Any limb amputations -weight >204kg (upper limit for DXA scanner) -Non-English speaking to provide consent -Unable to lie flat for 30 minutes

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026