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Comparison of pericapsular nerve group block and modified 3-in-1 block on postoperative pain level and speed of recovery after total hip arthroplasty

Comparison of pericapsular nerve group block and modified 3-in-1 block on postoperative pain level and speed of recovery after total hip arthroplasty

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12625001205426
Enrollment
41
Registered
2025-10-31
Start date
2025-03-18
Completion date
2025-12-24
Last updated
2025-11-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Primary purpose of the study is to compare efficacy of modified 3-in-1 block (femoral, lateral femoral cutaneous and obturator nerve) to pericapsular hip nerve group block (PENG block and lateral femoral cutaneous nerve block) on postoperative pain score in patients after total hip arthroplasty. We hypothesize that modified 3-in-1 block will provide longer duration of analgesia in comparison to control group (PENG block) while using smaller cumulative amount of anesthetic.

Interventions

3-in-1 block consists of the administration of local anesthetic around the obturator nerve (10ml 0.25% levobupivacaine), femoral nerve (10ml 0,125% levobupivacaine) and lateral femoral cutaneous nerve (5ml 0.25%). The block will be performed by an anesthesiologist upon entry to the operating room, prior to spinal anesthesia.

Sponsors

Vedran Lokosek - Department for anesthesiology, intensive care and pain management, Sestre milosrdnice University Hospital Center
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

ASA status 1 to 3 patients scheduled for total hip arthroplasty.

Exclusion criteria

patient refusal local anesthetic allergies previous lumbosacral syndromen in medical history patients taking chronic analgesic therapy

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026