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Breathing Evaluation using Advanced Technology in Health Examination A feasibility study of a new breathing test (passive spirometry) to identify lung problems compared with standard tests.

Feasibility study of passive spirometry methods in identifying modes and severities of respiratory dysfunction, compared to standard of care pulmonary function testing

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12625001196437
Acronym
BREATHE
Enrollment
100
Registered
2025-10-31
Start date
2026-02-02
Completion date
2026-04-25
Last updated
2025-11-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Computational models of lung have been developed to assess lung mechanics. Recently these methods have been developed to be identifiable in spontaneous normal breathing, where historical quantification of muscular effort and technological capacity limited these assessment methods. Bench testing these methods have been made using a mechanical test lung and healthy subjects have been tested at the low-risk clinical unit at the University of Canterbury. This study would be a pilot feasibility test in a clinical population to establish clinical efficacy to justify further testing and technology/methodology improvements.

Interventions

A new resting breathing pressure and flow measurement device with be tested (pressure and flow meter with a rapid expiratory occlusion (REO) valve. Where, computational models will be used to assess lung function parameters from the new device following the study. The subject will be instructed to breathe (at rest) through the device using the mouthpiece (similar to spirometry) by a researcher for 3-5 1 min recordings. This test will occur in the pulmonary physiology lab at Christchurch hospita

A new resting breathing pressure and flow measurement device with be tested (pressure and flow meter with a rapid expiratory occlusion (REO) valve. Where, computational models will be used to assess lung function parameters from the new device following the study. The subject will be instructed to breathe (at rest) through the device using the mouthpiece (similar to spirometry) by a researcher for 3-5 1 min recordings. This test will occur in the pulmonary physiology lab at Christchurch hospital after standard testing appointment (expected to add <10-15 minutes).

Sponsors

University of Canterbury
Lead SponsorUniversity

Study design

Allocation
Non-randomised trial
Intervention model
Other
Primary purpose
Diagnosis
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. are scheduled for pulmonary function testing at the Christchurch hospital pulmonary function laboratory 2. have a diagnosed chronic respiratory disease 3. can provide informed consent to participate in the trial (over 16 and competent)

Exclusion criteria

None

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026