None listed
Conditions
Brief summary
An impaired sense of smell impacts on an individual’s quality of life and safety. A reduced sense of smell is also linked to various brain diseases. The nerve cells in the nose that detect smell also respond mechanically to the rhythmic activity of nasal breathing and then set up brain wave activity. A small nasal breathing oscillation device that plugs into the nose to create nasal pressure oscillations has been developed. A previous pilot study assessing smell showed a reported subjective smell improvement (ACTRN12623001307695), however this study aims to further assess objective measures of sense of smell. The purpose of this pilot study is to assess whether when objective markers of smell are used, whether a persons’ sense of smell could be improved when the nasal breathing oscillation device is used regularly for four weeks.
Interventions
The small nasal breathing oscillation device plugs into the nose. The participants will be given in-person practical advice on how to place the device in the nose and used it. The device will deliver bilateral oscillations to the nose. An ear, nose and throat physician will provide the advice and also examine the participants noses prior to use. The nasal breathing oscillation device will be used regularly for a minimum of ten minutes twice a day for four weeks. .The participants will be asked
The small nasal breathing oscillation device plugs into the nose. The participants will be given in-person practical advice on how to place the device in the nose and used it. The device will deliver bilateral oscillations to the nose. An ear, nose and throat physician will provide the advice and also examine the participants noses prior to use. The nasal breathing oscillation device will be used regularly for a minimum of ten minutes twice a day for four weeks. .The participants will be asked to keep a diary, and the participants will be contacted weekly to monitor progress, ensure that they are using the device correctly, address any issues they might have, and to gather feedback on their experience.
Sponsors
Linsell Richards Educational Foundation
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
30 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
Self reported reduction in olfaction.
Exclusion criteria
1. Cigarette smoking 2. Moderate or severe nasal valve collapse 3. Medically treated allergic rhinitis 4. Grade 2-4 polyps 5. Recent upper respiratory illness 6. Nasal crusting or ulceration on rhinoscopy 7. A history of severe nose bleeding within last 3 months 8. Anticoagulant use 9. Known pregnancy 10. Allergic sensitivity to silicone or any other component of device 11. Inability to read and understand English.
Outcome results
None listed