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What happens in the brains of both the patient and the chiropractor during chiropractic care?

Neural Synchrony and Therapeutic Alliance: A Hyperscanning EEG Study in Chiropractic Care in the patient and the chiropractor

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12625001097437
Enrollment
30
Registered
2025-10-08
Start date
2025-10-13
Completion date
2025-11-28
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study will investigate how the relationship between a chiropractor and a patient may be reflected in their brain activity during treatment. Previous research in other healthcare settings has shown that when a strong connection is formed, both individuals’ brain activity can become synchronised in ways linked to attention and emotional understanding. Using a technique called hyperscanning EEG, brain activity from both chiropractor and patient will be recorded at the same time during a chiropractic session. This allows measurement of whether moments of synchrony occur and whether these are associated with better reported relationships, reduced pain, and higher satisfaction. The findings are expected to improve understanding of how the quality of the patient–practitioner relationship contributes to treatment outcomes in chiropractic care.

Interventions

Participants in the intervention group will receive chiropractic care (Single session), including spinal adjustments performed by a registered chiropractor. A registered chiropractor will assess the entire spine, and both sacroiliac joints will be assessed for vertebral subluxation by a registered chiropractor with at least five years of clinical experience. The clinical indicators that will be used to assess the function of the spine before spinal adjustment intervention include assessing for j

Participants in the intervention group will receive chiropractic care (Single session), including spinal adjustments performed by a registered chiropractor. A registered chiropractor will assess the entire spine, and both sacroiliac joints will be assessed for vertebral subluxation by a registered chiropractor with at least five years of clinical experience. The clinical indicators that will be used to assess the function of the spine before spinal adjustment intervention include assessing for joint tenderness to palpation manually palpating for a restricted intersegmental range of motion, assessing for palpable asymmetric intervertebral muscle tension, and any abnormal or blocked joint play and end-feel of the joints. Chiropractors use these biomechanical characteristics as clinical indicators of spinal dysfunction and vertebral subluxation. All spinal adjustments carried out in this study will be high-velocity, low-amplitude thrusts to the spine or pelvic joints, a standard adjusting technique used by chiropractors. The mechanical properties of chiropractic adjustment have been investigated; and although the actual force applied to the patient's spine depends on the chiropractor, the patient, and the spinal location of the subluxation, the general shape of the force-time history of spinal adjustments is very consistent and the duration of the thrust is always less than 200 milliseconds. The whole assessment and intervention will take around 45 minutes. EEG: EEG will be recorded before, during, and after the intervention session using a portable 64-channel, research-grade system (gel-based cap with active electrodes). Two separate EEG units will be used for the participants and the chiropractors, with caps appropriately sized for each wearer. A trained EEG researcher will apply, check impedances, and monitor the recording throughout, under the oversight of the study’s lead. The anticipated EEG monitoring duration during intervention is ~10-15 minutes per session, with continuous artifact monitoring and standard safety/hygiene procedures followed. Materials: Before enrolment, participants will receive a Participant Information Sheet and Consent Form (and a brief pre-visit guidance sheet), while treating chiropractors will use a standardized procedure checklist and case-report form aligned with the study rubric. Setting: All sessions will be delivered at the New Zealand College of Chiropractic (NZCC) Chiropractic Centre (Auckland). Adherence/fidelity: Because this is a single-session intervention, adherence will be defined as attendance and completion of the visit; this will be verified via clinic scheduling logs and a signed clinician checklist documenting each protocol step, with any deviations recorded in the case-report form.

Sponsors

New Zealand College of Chiropractic
Lead SponsorOther

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Inclusion Criteria: - Adults aged 18 years and above - Practice members with mild to moderate spinal musculoskeletal issues (e.g., neck, mid and lower back pain) seeking chiropractic care. - Ability to provide informed consent and tolerate EEG recording. - No prior EEG abnormalities or contraindications to manual therapy.

Exclusion criteria

Exclusion Criteria: - Have any contraindications to chiropractic adjustments (such as a history of recent spinal fractures, inflammatory disease such as rheumatoid arthritis, or a recent history of cancer). - Have any neurological disorder such as stroke, seizures - Have a history of head injury with ongoing symptoms. - Have metal implants in their head - Have severe psychiatric disorders (e.g., schizophrenia) - Are experiencing acute pain or serious injury needing urgent care - Have substance use disorders (ongoing problems related to alcohol or drug misuse) - Have major health conditions (e.g., heart disease) - Have a history of aggressive behaviour, suicidal thoughts, or difficulty cooperating.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026