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Secondary Knee Osteoarthritis - Pain Assessment and Functional Evolution after Rehabilitation

Assessment of Pain and Functional Evolution after 3-month in-home Rehabilitation in Former Football Players Diagnosed with Secondary Knee Osteoarthritis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12625001046493
Enrollment
43
Registered
2025-09-22
Start date
2025-05-12
Completion date
2025-09-22
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

To assess the clinical evolution of pain perception and joint function and quality of life in former male football players diagnosed with knee osteoarthritis, by comparing initial and final values of: - Visual Analogue Scale (VAS) at rest and during walking - Lequesne Index - Pressure Pain Threshold (PPT) measured with a pressure algometer - WOMAC scale

Interventions

The strategies used to monitor adherence to the intervention the session attendance, the VAS scale for pain, the Lequesne index, and the WOMAC scale for functionality – initial, when all patients were included in study and final, after 3 months. We`ll performed the following interventions for all patients: 1. Ultrasound Exam of the Knee (initial and after 3 months) • Supervisor/Provider: The exam is conducted by a qualified sonographer. • Mode of Administration: The examination is carried out o

The strategies used to monitor adherence to the intervention the session attendance, the VAS scale for pain, the Lequesne index, and the WOMAC scale for functionality – initial, when all patients were included in study and final, after 3 months. We`ll performed the following interventions for all patients: 1. Ultrasound Exam of the Knee (initial and after 3 months) • Supervisor/Provider: The exam is conducted by a qualified sonographer. • Mode of Administration: The examination is carried out on a one-on-one basis in a private setting where only the patient and the sonographer are present. • CARTILAGE THICKNESS – is a study parameter 2. Pressure Pain Assessment with Algometer (bilaterally at the knee using an Algometer II - SBMedic Electronics, Sweden; the probe - 1 cm² will be applied perpendicularly with pressure increasing at ~1 N/s until pain was reported). • Supervisor/Provider: This procedure is supervised and administered by a physiotherapist specialized in pain assessment and treatment. • Mode of Administration: The procedure is performed individually, with the physiotherapist applying pressure directly to the affected knee area to assess the patient's pain level. For areas will be investigated (superior, inferior, medial and lateral knee area) 3. Imagistic X-ray of the Knee: • Supervisor/Provider: The X-ray is performed by a radiologic technician. • Mode of Administration: The procedure is conducted individually in an X-ray room, where the patient is positioned appropriately to obtain the clearest possible images of the knee structure. • KELLGREN-LAWRENCE GRADE will be used to assess the knee osteoarthritis grade 4. Physical procedures (TENS, laser, ultrasound) administered by a physiotherapist in a clinical setting. • Transcutaneous Electrical Nerve Stimulation (TENS) of the quadriceps muscles and calf muscles (Endomed 482, device series 42.400, Enraf-Nonius, Netherlands); 30 min daily session of TENS for 6 days each week using two pairs of 10 cm × 15 cm carbon rubber electrodes (150 cm2), one for each side, stimulated both muscle groups, 15 minutes each region. • Low-Level Laser Therapy (LLLT) 20 minutes, daily (ASTAR PhysioGo 500I/501I Poland, PhysioGo series) Wavelength of 808 nm, a power of 100 mW, and an energy dosage of 7 J / cm2 , energy per point of 0.003 J. Applied for knee girdle muscles, left and right. • Ultrasound (BTL 4000). The treatment is carried out on an individual basis, where the patient is comfortably seated, and the ultrasound head (0.6 W/cm2) is moved in a circular motion over the affected knee area, for 10 minutes, left and right. 5. In-patient kinetic program (stretching, strength, aerobic training) administered by a physiotherapist in a clinical setting. - stretching of adductor and hamstrings muscles, daily, 10 minutes - strength exercises (gluteus medium and quadriceps), daily, 15 minutes - aerobic training (endurance training) performed at 60%–80% of maximum heart rate, according to the equation ((220 – age) × 0.65), three times a week, 40 minutes In-patient kinetic program occurs daily for the duration of hospital stay, as it was mentioned bellow. 6. Out-patient 3 months home-training; occurs 3 days after hospital discharge Aerobic training, three times a week, 40 minutes - Warm-up (10 minutes): gentle stretching and slow walking or stationary cycling - Main Activity (20 minutes): walking on flat surface or treadmill - Cool-down (10 minutes): slow walking and stretching Flexibility training, three times a week, 40 minutes - Warm-up (10 minutes): light cardiovascular exercise like walking or stationary cycling at a very low intensity. - Main Activity (20 minutes): Dynamic stretches: leg swings and arm circles to improve range of motion. Static stretches: hold stretches for each major muscle group for 20-30 seconds, such as hamstring and quadriceps stretches, and arm stretches. - Cool-down (10 minutes): Deep breathing and relaxation techniques to enhance muscle relaxation.

Sponsors

Filantropia Hospital Craiova
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment

Eligibility

Sex/Gender
Male
Age
45 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

1. Clinical and radiological diagnosis of secondary knee osteoarthritis 2. Former football players (with a minimum of 5 years of active participation in amateur or professional football) 3. Symptoms present for at least 3 months (e.g., pain, stiffness, reduced mobility) 4. Lequesne Index score = greater than or equal to 7 (mild to moderate functional impairment) 5. VAS pain score during walking = greater than or equal to 4 6. Measurable Pressure Pain Threshold (PPT) using a pressure algometer 7. Able to walk without permanent walking aids 8. BMI between 18.5 and 40 9. No intra-articular injections (corticosteroids, hyaluronic acid) within the last 3 months 10. No knee surgeries within the last 6 months 11. Ability to understand and sign the informed consent form

Exclusion criteria

1. History of total or partial knee arthroplasty 2. Presence of other significant musculoskeletal or neurological disorders affecting gait or joint function (e.g., rheumatoid arthritis, peripheral neuropathy) 3. Current opioid therapy or chronic use of strong analgesics 4. Severe obesity (BMI > 40) 5. Cognitive impairment or psychiatric disorders interfering with the ability to complete clinical assessments or follow the rehabilitation program 6. Recent trauma to the lower limbs (within the last 3 months) 7. Participation in another clinical trial within the last 30 days

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026