None listed
Conditions
Brief summary
Study aim: To assess the performance of different ultrasound enthesitis scoring systems in assessing disease activity of psoriatic arthritis. Study hypothesis: Ultrasound scores with more sites of examination and inclusion of acute lesions (tendon thickening, hypoechogenicity, and doppler signal) may be more closely associated with global disease activity in psoriatic arthritis.
Interventions
Musculoskeletal ultrasound to assess enthesitis in participants with psoriatic arthritis at baseline visit in Fiona Stanley Hospital/Harry Perkins Insitute of Research or Royal Perth Hospital. The ultrasound will be conducted at one study visit by Rheumatologist with experience with ultrasound. The ultrasound will last around 60 minutes and will involve 7 entheses sites (14 bilaterally) around the upper and lower limbs. Ultrasound will occur before clinical examination and patient questionnaires
Musculoskeletal ultrasound to assess enthesitis in participants with psoriatic arthritis at baseline visit in Fiona Stanley Hospital/Harry Perkins Insitute of Research or Royal Perth Hospital. The ultrasound will be conducted at one study visit by Rheumatologist with experience with ultrasound. The ultrasound will last around 60 minutes and will involve 7 entheses sites (14 bilaterally) around the upper and lower limbs. Ultrasound will occur before clinical examination and patient questionnaires. The images will be graded by the rheumatologist according to different scoring systems based on presence of altered echogenicity/structure, thickening, erosion, enthesophyte, bursitis and doppler signals Participants will be asked to avoid strenuous activity and taking any as needed steroids or anti-inflammatories on day of the visit. They will also be asked to avoid talking to the ultrasonographer about the status of their disease. There will be a separate researcher doing the physical examination and administering the patient questionnaires.
Sponsors
Southern Metropolitan Health Service
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
• Participants are 18 years or over • Participants who have been diagnosed with psoriatic arthritis • Able to give consent for study • At least one area of entheses tenderness (according to LEI or SPARCC).
Exclusion criteria
• Participants who are not able to cooperate with ultrasound examination – unable to follow instructions to lie supine and prone on examination bed. • Participants with other inflammatory arthritis, fibromyalgia and/or chronic pain syndromes.
Outcome results
None listed