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Effectiveness of hysteroscopic resection of a niche VERSUS Expectant management in women with premenstrual spotting postmenstrual spotting

Effectiveness of hysteroscopic resection of a niche VERSUS Expectant management in women with premenstrual spotting , A randomized controlled trial. .

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12625001008415
Enrollment
107
Registered
2025-09-11
Start date
2025-09-28
Completion date
2026-04-01
Last updated
2025-12-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

efficacy of hystroscpic resection of cesarean section niche for management purpose to improve post menstrual spotting .

Interventions

General or regional (spinal) anesthesia depending on the extent of the procedure and surgeon preference. duration of the intervention : 30 -60 minutes . surgeon : senior specialist of endoscopic surgery. *Positioning: Lithotomy position with appropriate padding to avoid nerve injury. Bladder should be emptied before the procedure. 3. Surgical Equipment: *Rigid hysteroscope (5–9 mm) with operative channel. *30° lens for better visualization. *Electrosurgical loop momopolar or bipolar resectoscope

General or regional (spinal) anesthesia depending on the extent of the procedure and surgeon preference. duration of the intervention : 30 -60 minutes . surgeon : senior specialist of endoscopic surgery. *Positioning: Lithotomy position with appropriate padding to avoid nerve injury. Bladder should be emptied before the procedure. 3. Surgical Equipment: *Rigid hysteroscope (5–9 mm) with operative channel. *30° lens for better visualization. *Electrosurgical loop momopolar or bipolar resectoscope . *Uterine distension medium (normal saline for bipolar or glycine for monopolar energy). *Cervical dilators, if necessary. *Fluid management system to monitor inflow and outflow.Cervical Dilation (if required): Gradual dilation up to size compatible with the resectoscope. 2. Diagnostic Hysteroscopy: Initial inspection of uterine cavity to locate the cesarean scar defect, usually found at the anterior lower uterine segment. 4. Identification of Niche: Appears as a pouch or depression at the scar site, often with retained blood or mucus. 5. Resection Steps: a. Resect the Inferior Edge: Use a bipolar loop or scissors to excise the fibrotic and overhanging inferior edge of the niche to improve drainage and eliminate the pocket. *Remove any granulation tissue or polypoidal growth inside the niche. *Avoid aggressive resection of the superior edge to minimize thinning of the overlying myometrium. c. Coagulation: Apply light coagulation to bleeding points, avoiding excessive energy near the uterine serosa. 6.Fluid Balance Monitoring: Monitor input and output of distension fluid to avoid fluid overload (especially with glycine). strategies to assess the adherence to the intervention is accurate record of operative notes.

Sponsors

Maternity and children hospital faculty of medicine Minia University
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

*Women aged 18–45 years. *History of at least one cesarean delivery. *Presence of a uterine niche on transvaginal ultrasound. *Complaints of postmenstrual spotting lasting >2 days per cycle. *Regular menstrual cycles

Exclusion criteria

Active pelvic infection *known coagulation disorders. *Intrauterine device in place. *Other causes of abnormal uterine bleeding (e.g., fibroids, polyps

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026