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Analysis of the cardiac electrical signals in patients with Atrial Fibrillation

Retrospective and Prospective Analysis of Intracardiac Electro-Anatomic Data in Patients with Atrial Fibrillation

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12625001004459
Acronym
The ICE-AF study
Enrollment
2
Registered
2025-09-10
Start date
2025-05-16
Completion date
2028-06-01
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Patients who experience atrial fibrillation (AF) have an elevated risk of cognitive impairment and/ or stroke, heart failure and death. Recently, early rhythm control has been shown to reduce stroke and mortality in patients with AF. This retrospective and prospective observational study seeks to characterise intracardiac anatomic and electrical connections in patients undergoing ablation for AF. The primary objective of our study is to analyse electro-anatomic data to improve understanding of AF and AF ablation.

Interventions

This study will be conducted retrospectively and prospectively to examine the 3D electro-anatomic maps and intracardiac signals of participants who have undergone AF ablation at the Lyell McEwin Hospital. A total of 400 electronic medical records will be accessed which includes both retrospective and prospective data. Electronic data will be collected to examine the 3D electro-anatomic maps and intracardiac signals of participants who have undergone AF ablation at the Lyell McEwin and Ashford

This study will be conducted retrospectively and prospectively to examine the 3D electro-anatomic maps and intracardiac signals of participants who have undergone AF ablation at the Lyell McEwin Hospital. A total of 400 electronic medical records will be accessed which includes both retrospective and prospective data. Electronic data will be collected to examine the 3D electro-anatomic maps and intracardiac signals of participants who have undergone AF ablation at the Lyell McEwin and Ashford Hospitals. A waiver of consent to collect retrospective data (5 years) for 200 patients is provided for this study (Central Adelaide Local Health Network Human Research Committee). Therefore, no patient contact or consent is required. Prospective data (n = 200) will be collected for five years from the start of the study (2024) until 2030 from participants who are booked for an AF ablation at the Lyell McEwin Hospital, Cardiology Department and Ashford Hospital. They will be informed about the study by one of the study investigators and required to provide Consent to collect data only. All participant data will be de-identified and given a unique study ID number.

Sponsors

The University of Adelaide
Lead SponsorUniversity

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Inclusion Criteria • 18 years and over. • Participants who have undergone ablation for AF or atrial tachyarrhythmias at the Lyell McEwin Hospital and Ashford Hospital between 2019 and 2030.

Exclusion criteria

Exclusion Criteria • No ablation performed

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026