None listed
Conditions
Brief summary
This study aims to determine whether the use of artificial intelligence for polyp detection during colonoscopy has additional benefit when used in combination with texture and colour enhancement imaging (TXI) - a new form of advanced endoscopic imaging technology. In our previous study comparing TXI to usual endoscopic imaging we demonstrated significant improvement in polyp detection with TXI (ACTRN12621000708853). Artificial intelligence has been shown in clinical trials to improve polyp detection. We are aiming to assess whether there is a glass ceiling on polyp detection where additional technology may not be of incremental benefit.
Interventions
The use of texture and colour enhancement imaging (TXI) - a form of advanced endoscopic imaging technology, in combination with artificial intelligence for the detection of colonic polyps. TXI is a 'push-button' technology included with Olympus endoscopy systems which will be set in use for the entire colonoscope withdrawal. Artificial intelligence (computer aided detection) is an additional system that can be added to the Olympus endoscopy system, which uses artificial intelligence to identify and highlight colonic polyps. The anticipated time of colonoscopy is approximately 20 minutes, with AI processing occurring in real time. The procedures will be performed by consultant gastroenterologists in both the intervention and control groups. The computer aided detection images will be incorporated into a single colonoscopy report completed by the gastroenterologist. The intervention will be delivered once at the time of colonoscopy and includes only the index colonoscopy. This will be performed at two tertiary centres in South Australia. Patients are not required to adhere to the intervention. All proceduralists are involved as associate investigators and aware of the trial protocol. The principal investigator will be providing oversight to ensure adherence.
Sponsors
Study design
Eligibility
Inclusion criteria
All patients presenting for colonoscopy at the Lyell McEwin Hospital or Modbury Hospital
Exclusion criteria
Coagulation disorders Significant comorbidity (severe heart failure, chronic kidney disease or chronic obstructive pulmonary disease) Pregnancy Personal history of inflammatory bowel disease Family history of polyposis or non-polyposis bowel cancer syndromes