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Registry assessing heart outcomes in patients with cancer (CORIS-1)

A case-control registry assessing heart outcomes in patients with cancer and without cancer (C)RIS-1)

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12625000986471
Acronym
CORIS-1
Enrollment
4000
Registered
2025-09-05
Start date
2025-10-24
Completion date
2030-08-31
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The purpose of this study is to collect data for cancer patients with heart risks and compare this data to other people without cancer. Who is it for? You may be eligible for this study if you are an adult who has either been diagnosed with cancer or has never been diagnosed with cancer. Study details Participants with cancer will take part in blood tests, echocardiogram, ECG, and vital sign assessments as part of their standard care and questionnaires, while participants without cancer will take the same asssessments of which results will be availabe through medical record or your treating team in many cases. All participants will also be asked to complete an interview at baseline and be followed up for 6 months, 12 months and 24 months which includes vital signs, blood tests, ECG, echocardiongram,and questonnaires. If the test results are available, we'll collect data through medical records, however it these are not available, participants are asked to do the tests. It is hoped that this study will help provide data that will be able to be used to reduce risk of side effects including the heart, while also reducing interruptions to cancer treatment.

Interventions

Patients' involvement is needed because this study is collecting data prospectively from medical record, treating teams, patients and CHeReL for linked data. In most case these data will be available from the treating team. If the data such as reaults of blood test, ECG or echocardiogram is not available, patients will be asked to do the tests. Data to be colleted are medical history, cancer type and status, cancer treatment, vital signs, medication, ECG, echogardiogram, cardiovacular risk fac

Patients' involvement is needed because this study is collecting data prospectively from medical record, treating teams, patients and CHeReL for linked data. In most case these data will be available from the treating team. If the data such as reaults of blood test, ECG or echocardiogram is not available, patients will be asked to do the tests. Data to be colleted are medical history, cancer type and status, cancer treatment, vital signs, medication, ECG, echogardiogram, cardiovacular risk factors, blood tests, diet, questionnaires, cardiovascular events and cause of death. Questionairres include short IPAQ, ECOG and PHQ-9 anticipated to take 15 minutes at enrollment, 12 months and 24 month. The overall duration is 24 months from time of enrollement.

Sponsors

University of Sydney
Lead SponsorUniversity

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Inclusion Criteria (cases): 1. Patients that are of 18 years of age and older. 2. The following oncological diagnoses a. Prostate, bladder, testicular, lung, breast, and colorectal cancers 3. Receiving cancer therapy or have received cancer therapy within the last 5 years 4. Patients are willing to follow up at the enrolling center. Inclusion Criteria (controls): 1. Participants that are of 18 years of age and older 2. No current or previous oncological diagnosis at baseline

Exclusion criteria

1. Patient will not be following up at the participating site 2. Incapacity to provide written informed consent due to reasons other than language barriers

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026