None listed
Conditions
Brief summary
The objective of this RCT is to evaluate whether arthroscopically administered local anaesthesia in patients undergoing an anterior cruciate ligament reconstruction and posteromedial meniscal repair results in significant effects on acute pain relief and lower consumption of oral analgesia.
Interventions
Intraoperative Injection of a weight-dependent dose of local anaesthaetics (LA) (ropivacaine, max 3mg/kg) into the posterior joint capsule of the knee in patients treated with an ACL reconstruction and posteromedial meniscal repair (intervention group). The weight-dependent doses used for the study, 0.75% ropivacaine: 1.5mg/kg for 60-80kg, 2.5mg/kg for 80-100kg, 3.0 mg/kg for >100kg body weight. The amount of LA will be administered after drilling the femoral ACL tunnels and before passing the A
Intraoperative Injection of a weight-dependent dose of local anaesthaetics (LA) (ropivacaine, max 3mg/kg) into the posterior joint capsule of the knee in patients treated with an ACL reconstruction and posteromedial meniscal repair (intervention group). The weight-dependent doses used for the study, 0.75% ropivacaine: 1.5mg/kg for 60-80kg, 2.5mg/kg for 80-100kg, 3.0 mg/kg for >100kg body weight. The amount of LA will be administered after drilling the femoral ACL tunnels and before passing the ACL graft into the joint.
Sponsors
Perth Orthopaedic and Sports Medicine Research Institute
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
• Adults aged minimum 18 years with MRI-confirmed ACL rupture and medial meniscus tear (case and control cohort) • Suitable candidates for ACLR (hamstrings, patellar tendon, peroneus longus, allograft) with posteromedial MR (all repair techniques, minimum of two sutures/anchors). • Minimum body weight of 60 kg. • Willingness to comply with follow-up visits and assessments.
Exclusion criteria
• Irreparable ACL/meniscal injury or tear patterns for ACL repair. • Concomitant need for repair of further ligaments/lateral meniscus of the affected knee. • Age below 18 years. • Previous surgeries to ipsilateral ACL/medial meniscus. • Presence of pre-operative history of chronic pain issues or chronic consumption of pain relief. • Infection. • Pregnancy and lactation. • A history of substance abuse, or current substance abuse problem • Absence of Informed consent.
Outcome results
None listed