TRansplant and Infectious diseases Biobank and rEgistry (TRIBE)

The TRIBE is a multicenter clinical registry and biobank which will prospectively collect and store clinical data and samples from transplant recipients. Clinical data and high-quality stored biospecimens will be linked, allowing improvements in the delivery of clinical care and support for translational and basic science research. TRIBE will collect the following data from transplant recipients: patient demographics, medical history, diagnoses leading to transplant, timing of transplant surgery, previous transplant history, donor details and post-transplant complications. Samples that may be collected from transplant recipients include bloods, stool, urine, saliva, cerebrospinal fluid, bronchoscopy samples, colonoscopy samples and allograft biopsy samples. In addition, TRIBE will collect clinical information about organ donors and link to enrolled participants for the purpose of reporting donor-derived infections. A waiver of consent will be sought for organ donors and clinical information about organ donors will be obtained via Donate Life Victoria (DLV). For transplant recipients, there are two pathways to that data and/or samples can be submitted to the TRIBE: (1) routine collection of data and/or samples at pre-determined times (e.g. pre-transplant, >100 days post-transplant, >12 months post-transplant) and (2) event-driven collection of additional clinical data and/or samples [e.g. at time cytomegalovirus (CMV) disease is diagnosed].