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Limb circumference, muscle strength and quality of life after Complete Decongestive Therapy with structured exercise among Breast cancer-related lymphedema patient

Limb Circumference, Muscle Strength and Quality of Life after Complete Decongestive Therapy with Structured Exercise Among Breast Cancer Related Lymphedema Patients

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12625000897460
Enrollment
40
Registered
2025-08-18
Start date
2025-10-01
Completion date
2026-05-07
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Primary purpose: To evaluate the effectiveness of CDT combined with structured exercise in reducing limb circumference, improving muscle strength, and enhancing quality of life among individuals with BCRL. Hypothesis 1. Combination CDT with structured exercise have a significant effect in reducing arm circumference compare to usual care among BCRL patients following 8-weeks of intervention. 2. There is significance different in muscle strength between BCRL patients received combination CDT with structured exercise strength compare to usual care among BCRL patients following 8-weeks of intervention. 3. There is significance different in QoL status between BCRL patients received combination CDT with structured exercise compare to usual care among BCRL patients following 8-weeks of intervention.

Interventions

a. A brief description of CDT component: Manual lymphatic Drainage (MLD) - Non-invasive massage technique that uses light, superficial and gentle strokes to mobilize oedema fluid with pumping, scooping, and rotary movement according to Vodder Technique Multilayer Compression bandaging - Multi-layered padding and short-stretch bandages are applied to the affected limb. Remedial exercise: includes active, rhythmic, repetitive, non-resistance exercises combined with breathing. These exercises co

a. A brief description of CDT component: Manual lymphatic Drainage (MLD) - Non-invasive massage technique that uses light, superficial and gentle strokes to mobilize oedema fluid with pumping, scooping, and rotary movement according to Vodder Technique Multilayer Compression bandaging - Multi-layered padding and short-stretch bandages are applied to the affected limb. Remedial exercise: includes active, rhythmic, repetitive, non-resistance exercises combined with breathing. These exercises consisted of diaphragmatic breathing exercise, active free exercise for shoulder movement, elbow movement, wrist and fingers. Skin Care and education 1. Understanding of breast cancer-related lymphedema - sign and symptom 2. Overview of CDT 3. Compression bandaging - how to wear, important of bandaging and care tips 4. Skin care and infection prevention 5. Self-management technique 6. Precaution measure in daily life The structured exercise is according to a study done by Corum et. al (2021), Omar et al (2019) and Kim et al (2010). Strengthening exercise while wearing a multilayer bandage. Repetition Intensity: 60% of their estimated one repetition maximum (1RM) with 3 set per day for each exercise Resistance exercise includes: • Triceps extension • Biceps curl up • Dumbbell floor fly • Dumbbell side raise • Lifting the arm forward • Wrist curl • Reverse wrist curl b) Intervention will be deliver by physiotherapist at the hospital involved c) Frequency and total duration of intervention: - weekly for 8 weeks, 60-90 minutes per participants d) mode of delivery: one to one e) strategies to assess adherence to the intervention: session attendance and log book

Sponsors

University Kebangsaan Malaysia
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment
Masking
Blinded (masking used) (Caregiver)

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

Participants' diagnosed with breast cancer related lymphedema (Stage 1 & 2) after breast cancer surgery, circumference difference of more than 2 cm between extremities

Exclusion criteria

a. bilateral upper extremities lymphedema b. presence of active cancer c. skin infection or radiotherapy burn in the affected extremity d. renal failure e. advanced heart failure f. participants in other fitness programs g. recurrent BC during treatment

Outcome results

None listed

Source: ANZCTR · Data processed: Jul 3, 2026