None listed
Conditions
Brief summary
The FAST Walk study is a multicentre prospective cohort study that aims to enrol 1672 participants in Canada and Australia. The FAST Walk study will evaluate the association of 6MWT distance and 3 tests completed before surgery with outcomes assessed at 30 days and 90 days after major non-cardiac surgery. The primary aim of the study is to determine whether preoperative 6MWT distance adds prognostic value to usual clinical factors for predicting 30-day major postoperative complications. We hypothesise that a 6MWT will improve prediction of complications are elective non-cardiac surgery.
Interventions
All interventions will administered by a trained member of the research team.
1. All participants will undergo a preoperative six-minute walk test and grip strength test face to face, and will take around 30 minutes to complete.
2. Baseline blood tests and an ECG will be performed.
3. Baseline questionnaires will be administered - MET-REPAIR, EQ-5D (5-level version), Patient-Reported Outcomes Measurement Information System (PROMIS) – 29 General Health Profile, Brief Resilience Scale (BRS), PRO
All interventions will administered by a trained member of the research team. 1. All participants will undergo a preoperative six-minute walk test and grip strength test face to face, and will take around 30 minutes to complete. 2. Baseline blood tests and an ECG will be performed. 3. Baseline questionnaires will be administered - MET-REPAIR, EQ-5D (5-level version), Patient-Reported Outcomes Measurement Information System (PROMIS) – 29 General Health Profile, Brief Resilience Scale (BRS), PROMIS Social Isolation Short Form 4a 3. Postoperative blood tests (and ECG is troponin is elevated) will be performed on days 1, 2 and 3, as long as the patient remains an inpatient. Data fidelity will be ensured by data autinign and oversight by a trial data steering committee.
Sponsors
University of Melbourne
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Diagnosis
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Age greater than or equal to 40 years 2. greater than or equal to 1 risk factors for postoperative complications 3. Elective non-cardiac surgery with expected post-surgery stay greater than or equal to 2 days 4. Preoperative 6MWT is feasible
Exclusion criteria
1. Endovascular surgery 2. Lower limb orthopedic surgery 3. Contraindications to 6MWT
Outcome results
None listed