None listed
Conditions
Brief summary
The objective of study is to establish efficacy and complications of intralesional verapamil for the treatment of keloids and hypertrophic scars. We included a total of 174 patients of more than 18 years of age with no history of congestive cardiac diseases. They were divided into group A, who received intralesional verapamil and group B who received triamcinolone. Total of 2 injections were given at monthly interval.. Patients were assessed at the beginning and then after 2 months after the treatment. efficacy was assessed using vancouver scar scale. efficacy will be labelled as positive if total score reduction 75% or more.
Interventions
Group A will be recieving intralesional verapamil injection 1ml(2.5mg) every month upto 2 months using 1ml subcutaneous syringe.Efficacy will be determined after 2 months of treatment.
The injections will be administered by a registered nurse.
The strategies that will be used to assess adherence to the intervention will be the use of same brand verapamil injection using sterile 1ml subcutaneous syringe & needle throughout the duration of study which will be strictly administered by a registered
Group A will be recieving intralesional verapamil injection 1ml(2.5mg) every month upto 2 months using 1ml subcutaneous syringe.Efficacy will be determined after 2 months of treatment. The injections will be administered by a registered nurse. The strategies that will be used to assess adherence to the intervention will be the use of same brand verapamil injection using sterile 1ml subcutaneous syringe & needle throughout the duration of study which will be strictly administered by a registered nurse who will be dedicated to this specific task under supervision .
Sponsors
Noor ul Huda working as resident in khyber teaching hospital Peshawar.
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used) (Outcomes Assessor)
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
both male and female age 18-60 years patients with kelois or hypertrophic scars
Exclusion criteria
patients with pregnacy or lactation patients with family history of keloids. patients with acromegaly patients with congestive cardiac disease
Outcome results
None listed