The effect of citrus sinensis (sweet orange) peel extract on serum glucose and lipids levels in patients with Type 2 Diabetes: A Randomised Control Trial.

The effect of Citrus sinensis peel extract on serum glucose and lipids levels in patients with T2DM aged 35 to 75 years: A Randomised control trial.

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12625000535471

Enrollment

175

Registered

2025-05-27

Start date

2024-02-01

Completion date

2024-07-11

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study was conducted to estimate the role of citrus sinensis peel extract as an anti-hyperglycemic and an anti-dyslipidemic agent in combination with standard medical therapy owing to its glucose and lipid lowering properties.

Interventions

T2DM Patients in the Study group will be given citrus sinensis peel extract prepared as powdered form and 500mg once daily for 6 months with 100ml water or plain yogurt as preferred by the patients. The participants will be asked to maintain a memo on their phone indicating that they took the capsule. They will continue their standard medical care (metformin for their diabetes and statins (any type) for their dyslipidemias.

Study design

Allocation

Randomised controlled trial

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

35 Years to 75 Years

Healthy volunteers

Inclusion criteria

All T2DM patients with dyslipidemias presenting to outdoor dept. on Metformin and Statins therapy

Exclusion criteria

Pregnancy Any previous Myocardial Infarction (MI) Type 1 diabetes Patients on Insulin therapy Any other comorbidities like liver or kidney failure

Outcome results