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Effect of Taurine Supplementation on 20-km Self-Paced Cycling Performance in the Heat

Effect of Taurine Supplementation on 20-km Self-Paced Cycling Performance of Trained Cyclists in the Heat

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12625000520437
Enrollment
14
Registered
2025-05-26
Start date
2025-05-26
Completion date
2025-10-27
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Taurine has been shown to influence core body temperature, sweat response and blood flow regulation during exercise. However, the majority of this research has been conducted with a primary focus of understanding the physiological effects during fixed-paced trials, with limited evidence on the effects of taurine on exercise performance in the heat. As such, this study aims to determine the effects of taurine supplementation on performance, as well as perceptual and physiological responses during a 20km self-paced cycling time trial. The study will complete by 14 trained male and female cyclists, age between 18-55 who are not currently accustomed to hot environments. Participants will complete three visits, including VO2max and familiarization, and two experimental trials. Experimental trials will be conducted in a double-blind, randomized, placebo-controlled, crossover fashion and involved 4-day supplementation of either 50 mg/kg of taurine or a placebo (50 mg/kg/bm of maltodextrin), prior to the performance trial. assigned. The performance trial will involve a self-paced 20km time trial in heat (36°C with 40% relative humidity). Core body temperature, sweat rate, heart rate and perceptual responses will be assessed prior to and during the experimental trials. This research seeks to elucidate the potential effects of taurine on athletic performance in the heat.

Interventions

The study will complete by 14 trained male and female cyclists, age between 18-55 who are not currently accustomed to hot environments. Participants will complete three visits, including VO2max and familiarization, and two experimental trials. Experimental trials will be conducted in a double-blind, randomized, placebo-controlled, crossover fashion and involved 4-days of oral supplementation of either 50 mg per Kg of body weight (mg/kg/bw) of taurine or a placebo (50 mg/kg/bm of maltodextrin) pr

The study will complete by 14 trained male and female cyclists, age between 18-55 who are not currently accustomed to hot environments. Participants will complete three visits, including VO2max and familiarization, and two experimental trials. Experimental trials will be conducted in a double-blind, randomized, placebo-controlled, crossover fashion and involved 4-days of oral supplementation of either 50 mg per Kg of body weight (mg/kg/bw) of taurine or a placebo (50 mg/kg/bm of maltodextrin) prior to the performance trial. Supplementation will occur each day over the 4-days. Participants will consume the taurine and placebo in powder form (mixed with water, juice or other drink). The supplement will be consumed at home by the participants. Participants will be asked to return unused supplement which will be weighed to assess compliance. To prevent carry-over effects between the two supplementation conditions, a 7 -day washout period will be implemented. The performance trial will involve a self-paced 20km time trial in heat (36°C with 40% relative humidity). Core body temperature, sweat rate, heart rate and perceptual responses will be assessed prior to and during the experimental trials.

Sponsors

Edith Cowan University
Lead SponsorUniversity

Study design

Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Educational / counselling / training
Masking
Blinded (masking used) (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years
Healthy volunteers
Yes

Inclusion criteria

Fourteen trained cyclists aged 18 to 55 years, who have not been accustomed to heat exposure in the past 14 days will be recruited for this study. These individuals will be physically active, indicated by a maximal oxygen uptake of at least 50 mL /kg/min for men and 40 mL/kg/min for women. Participants will complete an adult pre-exercise screening questionnaire prior to the study. Individuals with contraindications to exercise (as per the screening tool and guide) will be asked to seek medical approval from a health professional prior to their participation. Participants will also provide details on their physical activity levels, and lack of significant recent heat exposure. Those with significant recent exposure to heat will be excluded.

Exclusion criteria

Individuals with recent structured heat acclimatisation will be excluded . Individuals that do not meet the fitness criteria as per the inclusion criteria will be excluded. Individuals with contraindications to exercise (as per the screening tool and guide) will be asked to seek medical approval from a health professional prior to their participation.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026