Skip to content

Mobilisation and vasoactive infusions: An observational study of practice across critical care

Mobilisation and vasoactive infusions: An observational study of practice across critical care

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12625000518460
Enrollment
400
Registered
2025-05-23
Start date
2025-05-28
Completion date
2025-08-12
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Many patients admitted to the intensive care unit or acute coronary care unit require medications to support their blood pressure while they are unwell.. Currently, guidelines are unclear on how safe it is the move patients out of bed when they are on these medications. At Canberra Hospital, we regularly move patients out of bed on these medications. This study will collect information on what happens to patients when they move out of bed while their blood pressure is supported as part of normal care. This will give us information that will allow us to compare information from other hospitals and better inform guidelines on what is safe to do with this group of patients.

Interventions

This prospective, single centre observational study will be undertaken for all patients admitted to the ICU and Acute Coronary Care Unit (ACCU) at Canberra Hospital over a three-month period requiring vasoactive and/or inotropic infusions (noradrenalin, adrenalin, dobutamine, vasopressin, milrinone, metaraminol, levasemendin, isoprenaline). This study will measure: -mobility rates -dosage of drug administer prior, during and post mobilisation -level of mobilisation utilising ICU mobility scale -

This prospective, single centre observational study will be undertaken for all patients admitted to the ICU and Acute Coronary Care Unit (ACCU) at Canberra Hospital over a three-month period requiring vasoactive and/or inotropic infusions (noradrenalin, adrenalin, dobutamine, vasopressin, milrinone, metaraminol, levasemendin, isoprenaline). This study will measure: -mobility rates -dosage of drug administer prior, during and post mobilisation -level of mobilisation utilising ICU mobility scale -attachments and sedation medication dosages during mobilisation -SOFA score on day of mobilisation and 24 hours post -mobility rates -adverse events during mobilisation and 24 hours post -functional outcome at ICU discharge (Acute Care Index of Function). Observation measures will be taken for the highest level of mobility that day on infusions. Mobility will be defined as any attempt at out of bed mobility (sitting on the edge of the bed, standing, transferring, ambulating, passively transferred to chair). We propose an observational study as mobilisation of patients on vasoactive and inotropic agents is already considered routine practice by physiotherapists and nursing staff in these areas.

Sponsors

The Canberra Hospital
Lead SponsorHospital

Eligibility

Sex/Gender
All
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

All patients admitted to ICU/ACCU at Canberra Hospital requiring vasoactive and inotropic infusions during the study timeframe

Exclusion criteria

• <16 years old • Admitted to ICU for end-of-life care • Medical conditions requiring prescribed bed rest by a medical officer (e.g. spinal precautions, post operative orders)

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026