Determining the accuracy of continuous glucose monitoring during periods of acute glycaemic variability in pregnancy

This study aims to assess the accuracy of continuous glucose monitoring (CGM) during periods of acute glycaemic variability in pregnancy, such as during hospital admission for acute illness or labour with or without betamethasone infusion. During hospitalisation, blood glucose monitoring will follow standard hospital protocols, which rely exclusively on capillary blood glucose measurements. While pregnant women often continue wearing their personal CGM devices during hospital stays, particularly those already using them as outpatients, CGM data will not be used to guide clinical decisions. All inpatient diabetes management, including insulin dosing, will be based solely on capillary blood glucose readings, in accordance with current standards of care. Participants were informed of this and encouraged to continue wearing their CGM devices during hospitalisation to support study data collection. Blood glucose checks will typically be performed 5–6 times daily for patients on multiple daily insulin injections (MDI), and hourly for those on intravenous insulin infusions, with increased frequency (every 30 minutes) if glucose levels fall outside target ranges. Some participants may receive betamethasone infusion during their hospital stay, independent of study involvement. Importantly, no study-related glucose monitoring will occur at home following discharge after birth.