None listed
Conditions
Brief summary
It has been suggested that endometriosis, being a hormone dependent disease, is worsening during ovarian stimulation treatments. several studies observed the imaging and clinical effects of these treatments but none of which investigated this worsening in comparison to general population. Our study aims to confirm or refute the assumption that endometriosis patients suffer more during ovarian stimulation. should we confirm this finding- that can be the bases of new field of research aiming to tailor a proper ovarian stimulation treatment for this population.
Interventions
Observational study on IVF patients undergoing ovarian stimulation for reproductive, medically acceptable, reasons- research group includes patients with endometriosis and control group includes patients with no diagnosis or clinical suspicion of endometriosis.
The medical process is according to acceptable IVF protocols. To evaluate our hypothesis we will use questionnaires regarding the degree of different symptoms, using a VAS score, during the time of ovarian stimulation at several key poin
Observational study on IVF patients undergoing ovarian stimulation for reproductive, medically acceptable, reasons- research group includes patients with endometriosis and control group includes patients with no diagnosis or clinical suspicion of endometriosis. The medical process is according to acceptable IVF protocols. To evaluate our hypothesis we will use questionnaires regarding the degree of different symptoms, using a VAS score, during the time of ovarian stimulation at several key points during the process as follow: 1. The day they joined the study 2. Five days after initiation of ovarian stimulation 3. The day of oocyte retrieval 4. One month after oocyte retrieval. ** the questionnaires will take approximately 10 minutes to answer each time. Total observation time is 2-3 month (depends on the time between the enlistment date and the oocyte retrieval).
Sponsors
Hadassah medical center
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
all patients undergoing IVF / ovarian stimulation for acceptable medical indications for their own free will can participate in this study according to the following devision: Inclusion criteria for the research group- patients with a surgical or imaging diagnosis of endometriosis. Inclusion criteria for the control group- Patients without diagnosis of endometriosis
Exclusion criteria
general exclusion criteria are- patients planning an immediate pregnancy, patients with othe pain disorders (such as fibromialgia), patients disappearing from the neccessery 1 month post retrieval follow-up. in addition, to following exclusion criteria are: exclusion criteria for the research group- Patients with only a clinical suspicion of endometriosis, without a surgical or imaging proof of it. exclusion criteria for the control group- patients with mechanical related infertility, patients with unexplained infertility, patients suffering from symptoms suspicious for endometriosis (as assessed by a simple questionnaire filled at the day of enrollment).
Outcome results
None listed