None listed
Conditions
Brief summary
DALE is a prospective, multi-site registry and biorepository, established to facilitate the collection of clinical data and biospecimens with the aim of furthering drug allergy research. Research questions which may be addressed relate to the epidemiology of drug allergy, our mechanistic understanding of the immune response to drugs in allergic patients, predictors of true or false drug allergy, diagnostic methods to identify causative drugs and quality of care in the management of drug allergy and delabelling.
Interventions
Patients with a reported drug allergy that have been reviewed clinically as an inpatient or outpatient at participating centres will be included in the registry through a waiver of consent, both retrospectively and prospectively. Demographic, medical history, allergy history and allergy testing results will be included. Participants may also be invited to participate actively by donating research samples including blood, skin biopsy, blister fluid for immunological analysis at baseline, 3 months
Patients with a reported drug allergy that have been reviewed clinically as an inpatient or outpatient at participating centres will be included in the registry through a waiver of consent, both retrospectively and prospectively. Demographic, medical history, allergy history and allergy testing results will be included. Participants may also be invited to participate actively by donating research samples including blood, skin biopsy, blister fluid for immunological analysis at baseline, 3 months and 12 months post-enrolment. These active participants will also be requested to complete the DrHy-Q at baseline and 12 months post-enrolment. Any pre-existing drug allergy data from the medical record will be reviewed and may be collected retrospectively.
Sponsors
The University of Melbourne
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patients with a reported drug allergy
Exclusion criteria
Nil
Outcome results
None listed