None listed
Conditions
Brief summary
The CONUT score is a scoring system used to assess immuno-nutritional status, incorporating values of albumin (g/dL), total lymphocyte count (count/mm³), and total cholesterol (mg/dL). The CONUT score is an efficient, accurate, and user-friendly tool for early detection and continuous monitoring of hospital malnutrition. Total cholesterol reflects calorie deficiencies; albumin indicates protein reserves; and lymphocyte count represents immunological defense. A high score, resulting from decreased values in each component, indicates poor nutritional status. Albumin plays a role in various functions such as nutrition, molecular transport, and colloid pressure. Malnutrition hinders lymphocyte formation and reduces circulating lymphocyte counts. Inflammation can induce Type 2 diabetes by increasing insulin resistance, and hyperglycemia can exacerbate inflammation, creating a vicious cycle. The net effect may manifest as increased long-term complications and mortality in diabetes. In conclusion, close monitoring of immuno-nutritional status and appropriate nutritional care in diabetic patients may contribute to improved prognosis. Therefore, we aimed to evaluate the relationship between CONUT score and immuno-malnutrition status in diabetic patients to determine 30-day mortality.
Interventions
The CONUT (Controlling Nutritional Status) score is a widely used screening tool for assessing the nutritional status of individuals in clinical practice. This score is calculated based on three biochemical parameters:
Serum albumin level: A marker of protein reserves.
Total lymphocyte count: An indicator of cellular immune function.
Total cholesterol level: A reflection of energy reserves.
The CONUT score is derived from the combination of these three parameters. A total CONUT score >2 is consi
The CONUT (Controlling Nutritional Status) score is a widely used screening tool for assessing the nutritional status of individuals in clinical practice. This score is calculated based on three biochemical parameters: Serum albumin level: A marker of protein reserves. Total lymphocyte count: An indicator of cellular immune function. Total cholesterol level: A reflection of energy reserves. The CONUT score is derived from the combination of these three parameters. A total CONUT score >2 is considered indicative of a risk for malnutrition, while a score of <2 is regarded as normal nutritional status. Serum albumin concentration, total lymphocyte count and total cholesterol data will be recorded in blood samples collected from patients at designated time points on day 0, week 1, week 2 and month 1 during admission to the intensive care unit and throughout follow-up. In addition, the thickness of the rectus femoris muscle will be measured using ultrasound by an anesthesiologist who has performed at least 50 measurements.
Sponsors
Berrak Sebil Aydin MD (Department of Anaesthesiology and Reanimation, Karadeniz Eregli Government Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
-Patients aged between 18 and 99 -Patients diagnosed with diabetes -Patients requiring ICU admission
Exclusion criteria
-Patients with a history of leukemia/lymphoma or a diagnosis of malignancy -Patients with a history of drug use that may cause bone marrow depression -Patients with a history of cirrhosis -Pregnant women -Patients with incomplete laboratory data -Patient with dialysis
Outcome results
None listed