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Does Blastx accelerate wound closure in chronic burn injuries?

Prospective randomised phase 4 clinical trial of the effect of Blastx on wound closure rates in chronic burn injuries

Status
Not yet recruiting
Phases
Phase 4
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12625000400460
Enrollment
126
Registered
2025-05-02
Start date
2025-05-05
Completion date
2025-08-31
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

We hypothesize that Blastx accelerates wound closure rates faster than Aquacel Ag Extra Plus on chronic burn wounds with better scarring outcomes. To test this theory, we will recruit patients with >4-week-old burn injuries and place them on an arm of the study, Comparing results and outcomes with the aid of AI technology and POSAS scores

Interventions

Patients with burn in juries >4 weeks old will be allocated into 2 arms of the study. The trial arm will be having 3mm thick blastx wound gel applied directly to the burn wound by burns nurses in clinic. This will htne be covered with a non-adherent pad. Patients will have Blastx applied to the burn twice a week with wound measurement occurring via photography with AI intelligence.. This will continue until wound closure.

Sponsors

Concord Hospital
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Primary purpose
Treatment

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

patient aged 18 years and over, burns that are >4 weeks old, burns managed by Burns team and burns that involve <1% Total body surface area (TBSA).

Exclusion criteria

patients aged 17 years and under, burns under 4 weeks old, burns sustained to specific anatomical locations, patients unable to perform informed consent or are receiving telehealth care.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026