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The effect of ethnicity on Meal Induced Thermogenesis (MIT study)

The effect of ethnicity on Meal Induced Thermogenesis (MIT) in adults with Asian or Caucasian ethnicity

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12625000345482
Enrollment
14
Registered
2025-04-23
Start date
2024-07-19
Completion date
2025-12-31
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of this study is to look at how much energy the body uses to digest, process and store the food that is eaten after a meal (referred to as meal -induced thermogenesis) and if there are differences between ethnicities. Understanding how the body uses energy may help us towards explaining observed differences in body composition (fat and lean mass) between people of Asian and Caucasian ethnicities and susceptibility of developing chronic diseases. The hypothesis is Asians will have a lower meal induced thermogenesis compared with Caucasians.

Interventions

The standard breakfast meal consists of a muesli bar, chocolate breakfast drink, and a bowl of oats (2524kJ, 55% carbohydrates, 13.2% protein, 27.5% fat). Participants will have 15mins to consume the breakfast meal and adherence is assessed using direct observation. The outcome observed is energy expenditure above resting metabolic rate (i.e. meal induced thermogenesis) for four hours after the standard breakfast meal in people of Asian ethnicity compared with people of Caucasian ethnicity. T

The standard breakfast meal consists of a muesli bar, chocolate breakfast drink, and a bowl of oats (2524kJ, 55% carbohydrates, 13.2% protein, 27.5% fat). Participants will have 15mins to consume the breakfast meal and adherence is assessed using direct observation. The outcome observed is energy expenditure above resting metabolic rate (i.e. meal induced thermogenesis) for four hours after the standard breakfast meal in people of Asian ethnicity compared with people of Caucasian ethnicity. The resting metabolic rate and meal induced thermogenesis of the participant will be measured using indirect calorimetry by an experienced researcher.

Sponsors

Monash University, Department of Nutrition, Dietetics and Food
Lead SponsorUniversity

Study design

Allocation
Non-randomised trial
Primary purpose
Diagnosis

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

• Aged 18-40 years old • Asian or Caucasian ethnicity • Healthy weight BMI 18.5kg/m2 - 23kg/m2 if you are Asian; or BMI 18.5kg/m2 – 24.9kg/m2 if you are Caucasian • Weight stable (within +/-2kg in the last 6 months) • Non-smoker and not vaping • Not pregnant or breastfeeding • Not on any medications known to alter body composition or metabolism (e.g. thyroxin, insulin, antidepressants, glucocorticoids) • Not have any food allergies or intolerances (e.g. lactose, gluten) • Not diagnosed with, and not on drug therapy for diabetes, high blood pressure, high cholesterol or cardiovascular disease

Exclusion criteria

None

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026