The effect of body weight on outcomes in elderly patients with critical illness

Conditions

None listed

Brief summary

This retrospective, observational cohort study will include nonagenarians admitted to the ICU between 2010 and 2023 across Australia and New Zealand. The study will utilise data from the Australian and New Zealand Intensive Care Society (ANZICS) Adult Patient Database. Who is it for? You are eligible if you are greater than 90 years old and admitted to ICI. Patients will be categorized into those with a normal body mass index and thiose with either a high or low body mass index. Study details This study will evaluate the short-term effects of body mass index on ICU and hospital mortality, length of stay, and mortality-associated factors. We hope these findings will emphasise the importance of shared decision-making that respects patient autonomy and considers clinical, cultural, and systemic factors.

Jake V. Hinton, Nattaya Raykateeraroj, Chin Jin Ker, Boris Waldman, Joohyun Suh et al. (9 authors)

Anaesthesia Critical Care & Pain Medicine2025-10-01

10.1016/j.accpm.2025.101634

Interventions

In this study we will be observing the postoperative outcomes in patients aged greater than 90 years who have been at admitted to Intensive Care Unit (ICU) across Australia and New Zealand. The main outcome being observed is hospital mortality. Secondary outcomes include ICU mortality, invasive treatments prescribed in ICU, including mechanical ventilation, renal replacement therapy, and use of vasoactive medications and inotropes. The duration of observation will be from ICU admission to deat

In this study we will be observing the postoperative outcomes in patients aged greater than 90 years who have been at admitted to Intensive Care Unit (ICU) across Australia and New Zealand. The main outcome being observed is hospital mortality. Secondary outcomes include ICU mortality, invasive treatments prescribed in ICU, including mechanical ventilation, renal replacement therapy, and use of vasoactive medications and inotropes. The duration of observation will be from ICU admission to death in either ICU or hospital. The exposure will include nonagenarians who are underweight (body mass index < 18.5 kg/m2), or overweight (body mass index between 25.0 kg/m2 and 30.0 kg/m2. Data will be extracted from the Australian and New Zealand Intensive Care Adult Patient Database for patients admitted to the ICU between 2010 and 2023.

Eligibility

Sex/Gender

All

Age

90 Years to No maximum

Healthy volunteers

No

Inclusion criteria

Inclusion criteria will be patients aged >90 years and <100 years who require an admission to the ICU for any indication.

Exclusion criteria

None

Outcome results