None listed
Conditions
Brief summary
Background and Rationale: Clinical trials are pivotal in advancing stroke care, yet participation remains low, exacerbating disparities, especially across age and gender demographics. This study aims to investigate the barriers to and facilitators of participation in clinical trials to enhance person-centred approaches in stroke research. Objectives: 1.To analyse the trends in age, gender, and rationales for non-participation in clinical trials among adult patients with stroke over the past 6 years at a tertiary Hospital in a large metropolitan area of Australia. 2.To develop and refine frameworks for patient recruitment that reduce barriers and enhance facilitation in stroke clinical trials. Study Design: A retrospective observational study complemented by a qualitative analysis of existing data from stroke patients who were eligible for clinical trial participation from January 2019 to January 2025.
Interventions
Observational - Retrospective analysis of existing patient data focusing on factors affecting clinical trial participation.
1) This study is collecting data retrospectively from medical records,
2) what is being observed in participants,
- Basic demographics including age, race, and gender at birth
- Diagnosis including onset of stroke and severity
- Previous health history, commorbidites
- social history
-Baseline Glasgow Coma Scale (GCS), and National Institutes of Health Stroke Scale
Observational - Retrospective analysis of existing patient data focusing on factors affecting clinical trial participation. 1) This study is collecting data retrospectively from medical records, 2) what is being observed in participants, - Basic demographics including age, race, and gender at birth - Diagnosis including onset of stroke and severity - Previous health history, commorbidites - social history -Baseline Glasgow Coma Scale (GCS), and National Institutes of Health Stroke Scale (NIHSS); GCS and NIHSS upon presentation to the hospital; and GCS and NIHSS upon approaching the patient for participation of clinical trial. - Discharge destinations - Retrospective data of suitability for Stroke Clinical Trials at a tertiary hospital in Melbourne CBD - Reasons why patients who are eligible for clinical trials have refused for the enrolment of the study 3) No questionnaire will be involved as this is a retrospective observational study. A lldata needed are already collected, 4) The source and time period (minimum month and year) this retrospective data was collected, - January 2019 - January 2025
Sponsors
Primary Investigator - Pamela Galindo, The Alfred Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
a) Adults aged 18 years or older. b) Diagnosed with stroke and considered for participation in clinical trials from January 2019 to January 2025.
Exclusion criteria
None, apart from clinical trial-specific exclusions documented in patient records.
Outcome results
None listed