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Effectiveness of three manual toothbrushes with different bristle designs in terms of plaque removal and gingival inflammation-A Randomized Controlled Trial

Effectiveness of three manual toothbrushes with different bristle designs in terms of plaque removal and gingival inflammation-A Randomized Controlled Trial

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12625000213448
Enrollment
105
Registered
2025-02-21
Start date
2021-04-08
Completion date
2021-04-08
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The purpose of the study was to compare the effectiveness of plaque control and reduction in gingival inflammation of three different toothbrush bristle design. Hypothesis: Advanced bristle designed toothbrushes (Crisscross and Zigzag) are effective in plaque control and gingival inflammation than that of conventional (Flat) bristle designed toothbrush.

Interventions

In this study three manual toothbrushes were distributed to each individual on baseline( day 0 ) The toothbrushes were of same company i; e Oral B and all were of soft bristle type. The toothbrushes were: i) Oral B Pro Health- Crisscross bristle designed toothbrush ii) Oral B Shiny Clean - Zigzag bristle designed toothbrush iii) Oral-B-Sensitive Care - Flat bristle designed toothbrush With toothbrushes a fluoridated toothpaste was also distributed i.e., Closeup Triple formula anti-germ gel toot

In this study three manual toothbrushes were distributed to each individual on baseline( day 0 ) The toothbrushes were of same company i; e Oral B and all were of soft bristle type. The toothbrushes were: i) Oral B Pro Health- Crisscross bristle designed toothbrush ii) Oral B Shiny Clean - Zigzag bristle designed toothbrush iii) Oral-B-Sensitive Care - Flat bristle designed toothbrush With toothbrushes a fluoridated toothpaste was also distributed i.e., Closeup Triple formula anti-germ gel toothpaste red hot-80 gm at the baseline of the study. The overall mean scores of Plaque Index and Gingival index were measured at baseline, 7, 14 and 21 days. Participants were separated in three groups and each group had only received one of the three toothbrush. Participants were instructed to use one type of toothbrush for 21 days, twice a day for 2 minutes. for the adherence or compliance, participants were monitored time to time in brushing time by an individual other than the researcher herself.

Sponsors

principal author [ Dr. Ratna Mishal], Madan Bhandari hospital and trauma center, Urlabari
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Blinded (masking used) (Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
All
Age
18 Years to 27 Years
Healthy volunteers
No

Inclusion criteria

1. Individual having Plaque and Gingival score at least 1 2. Individual having at least 5 teeth (excluding third molar) in each quadrant with facial and lingual scorable surfaces

Exclusion criteria

1. Individual with systemic illness 2. Individual with orthodontic appliances 3. Individual requiring any emergency dental treatment 4. Individual not willing to participate in the study 5. Individual with advanced periodontal disease 6. Individual with a history of antibiotic usage or using antibiotic 7. Individual taking any oral prophylactic agents.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026