None listed
Conditions
Brief summary
This study investigates the effects of an energy-restricted Mediterranean diet on telomeres in overweight and obese individuals. It includes female participants aged 20-50 at Gazi University, Türkiye, over an eight-week period. Data on demographics, dietary records, body composition, anthropometric measurements, and physical activity levels are collected. The Mediterranean Adequacy Index (MAI) is calculated at the beginning and end of the study. Participants follow an individualized energy-restricted Mediterranean diet. Biochemical parameters such as glucose, HDL-C, LDL-C, Total-C, C-reactive protein, TNF-a, IL-6, TAS, TOS, and telomere length are analyzed.
Interventions
Energy Restricted Mediterranean Diet is given to patients by dietician. They will be asked to consume Energy-restricted Mediterranean diet with 50-60% carbohydrates, 15-20% protein, and 25-30% fat. Diet lists were prepared by the dietician for the individuals participating in the study to consume Mediterranean diet for 8 weeks. According to personal preferences, daily planning was made as "3 main meals and 3 snacks" or "3 main meals and 2 snacks". Participants received training on the Mediterranean diet pyramid and recommendations for weekly and daily food group consumption. Diets were organized to ensure a Mediterranean diet score of at least 11 according to "Stefler D, Malyutina S, Kubinova R, Pajak A, Peasey A, Pikhart H, et al. Mediterranean diet score and total and cardiovascular mortality in Eastern Europe: the HAPIEE study. Eur J Nutr. 2017;56(1):421–9. ". The duration of the intervention is 8 weeks. The administration of the diet is done by dietician by face to face consultation. To assess the dietary adherence and body weight loss of the overweight and obese group, the researcher conducted biweekly interviews, monitored their body weight and composition, and engaged in weekly phone calls to evaluate their compliance with the diet and provide motivation. The dietitian assessed the individuals face-to-face with approximately half-hour interviews once every 15 days for 8 weeks. Telephone calls for evaluation and motivational purposes are approximately 15 minutes per week.
Sponsors
Study design
Eligibility
Inclusion criteria
Female participants between aged 20-50, with a BMI between 25-29.9 kg/m2(overweight group) (n=14), greater than 30 kg/m2(obese group) (n=14), and who applied to the Nutrition and Dietetics Clinic of Gazi University, Faculty of Health Sciences, Department of Nutrition and Dietetics, were included in the study.
Exclusion criteria
smoking, chronic diseases except for hyperlipidemia and hypertension, males, pregnant females, breastfeeding females, heavy exercisers, vitamin-mineral supplements or nutritional supplement users, and having another special diet.