Outcomes of meningomyelocele repair with or without platelet rich plasma application

To compare outcome of meningomyelocele repair with or without platelet rich plasma in terms of preventing cerebrospinal fluid leakage, meningitis and wound infection. During meningomyelocele repair, a neural plate was formed and watertight dural closure was done. After achieving hemostasis, Platelet rich plasma was applied over dural repair and wound edges. b) Platelet rich plasma will be obtained by centrifugation at 200 g at 22 degree celcius for 10 minutes. Then uppermost layer will again be transferred into another centrifugation tube by using sterile pipette and this will again centrifugate at 400g at 22 degree celcius . Around 1ml of Platelet rich plasma will be obtained by this two step method. All this will be done pre operatively to save time. c) Surgeon will do the intervention. d) Intervention requires fifteen to thirty minutes. e) Direct observation of the surgery is required to assess adherence to surgery