Treatment of Urinary Tract Infection with Intravenous Antibiotics at Home, as an Alternative to Ward based care by Hospital in the Home (HITH) Services for patients in Australian Capital Territory (ACT)

Is treatment of UTI with intravenous antibiotics at home via HITH at least as safe and effective as on the ward? A retrospective clinical audit of UTI patients admitted to ACT HITH services

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12625000172404

Enrollment

357

Registered

2025-02-13

Start date

2025-02-17

Completion date

2025-03-31

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of this project is to demonstrate that for patients with a UTI in whom intravenous antibiotic therapy is clinically indicated, there is a subset of these patients who can be safely managed at home by Hospital in the Home (HITH). The hypothesis is that HITH treatment for appropriately chosen patients with UTI has comparable (or even better) clinical outcomes when compared to available data on UTI treatment in a hospital ward setting in terms of length of stay, morbidity and mortality. It also aims to determine what patient factors may be associated with prolonged length of stay and poorer clinical outcomes. How well antibiotic prescription concurs with recommended antibiotic prescribing practices will also be assessed

Interventions

Retrospective outcomes audit on patients admitted to the 2 Australian Capital Territory (ACT) Hospital in the Home (HITH) services (The Canberra Hospital HITH and North Canberra Hospital HITH) between Nov 2022 to June 2024 for the purpose of IV antibiotic treatment for urinary tract infection (UTI). Prior 12 month audit on same at TCH HITH only (71 patients), showed that patient outcomes in HITH were comparable to those published in the literature for similar patient cohort admitted to hospital wards for purpose of IV antibiotic treatment for UTI. Measured outcomes will be mortality, hospital ward readmission rate during HITH admission and at 30 days post discharge (and reason for same), admission length of stay, including proportion of time spent in HITH versus ward, adherence to local and national antimicrobial resistance guidelines, demographic details/co-morbidities/investigation results/procedures/urological devices recorded to enable exploration of patient risk factors that could be associated with a longer length of stay to further assess complication and readmission rates

Eligibility

Sex/Gender

All

Age

16 Years to No maximum

Healthy volunteers

Inclusion criteria

All adult patients admitted to The Canberra Hospital or North Canberra Hospital HITH services for the purpose of IV antibiotic administration for UTI, whether for all or part of the entire hospital inpatient admission from November 2022 to June 2024

Exclusion criteria

No exclusion criteria being retrospective audit study

Outcome results